Results 61 to 70 of about 2,903,653 (291)

Managerial Talent, Motivation, and Self-Selection into Public Management [PDF]

open access: yes
The quality of public management is a recurrent concern in many countries. Calls to attract the economy’s best and brightest managers to the public sector abound.
Delfgaauw, Josse, Dur, Robert
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Evaluation of a digital consultation and self-care advice tool in primary care: a multi-methods study [PDF]

open access: yes, 2018
Digital services are often regarded as a solution to the growing demands on primary care services. Provision of a tool offering advice to support self-management as well as the ability to digitally consult with a General Practitioner (GP) has the ...
Eileen Calveley   +6 more
core   +4 more sources

Self-Learning Classifier for Internet traffic [PDF]

open access: yes, 2012
Network visibility is a critical part of traffic engineering, network management, and security. Recently, unsupervised algorithms have been envisioned as a viable alternative to automatically identify classes of traffic. However, the accuracy achieved so
Baralis, Elena Maria   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The impact of emotion management ability on learning engagement of college students during COVID-19

open access: yesFrontiers in Psychology, 2022
During the COVID-19, the wanton spread of novel coronavirus had a huge negative effect on the emotions of college students, resulting in a serious impact on the daily learning behavior of many college students.
Xiaochun Lei
doaj   +1 more source

Longitudinal Investigation of Older Adults' Ability to Self‐Manage Complex Drug Regimens

open access: yesJournal of the American Geriatrics Society, 2019
OBJECTIVES We sought to investigate older patients' ability to correctly and efficiently dose multidrug regimens over nearly a decade and to explore factors predicting declines in medication self‐management. DESIGN Longitudinal cohort ...
Stacy Cooper, Bailey   +6 more
openaire   +3 more sources

Acculturation is associated with older Turkish immigrants’ self-management abilities [PDF]

open access: yesBMC Public Health, 2019
The few previous studies investigating acculturation and self-management have suggested that increased participation in (or adaptation to) the host culture is associated with better health and disease management. However, research on the relationship between acculturation strategies (attachment to the Dutch and Turkish cultures) and broader self ...
Cramm, Jane Murray, Nieboer, Anna Petra
openaire   +3 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Factors contributing to effective language laboratory use in New Zealand tertiary institutes : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Japanese at Massey University [PDF]

open access: yes, 1998
This study focuses on how language laboratories in New Zealand tertiary institutes can be used more effectively. The language laboratory is an excellent tool of learning which can be used to aid the development of both listening and speaking skills as ...
Nesbitt, Dallas
core  

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