Results 41 to 50 of about 5,501,143 (256)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Indonesian authors’ stances in citing English research article introductions literature in sciences
Edulite: Journal of English Education, Literature, and Culture, 2018 Authorial stance is an important aspect in academic texts in academic texts such as research articles (RAs); that is to show the attitude of authors toward the information cited in a reference in order to establish an argument.
Suci Miasari, Safnil Arsyad, Arono Arono
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
The 'Operational' Definition of Self-Control [PDF]
, 2018 Self-control is a hot topic across disciplines. As such, consensus on defining self-control is critical for advancing both scientific progress as well as societal impact of research findings.
Stress and self-regulation +3 more
core +1 more source
Metadiscursive Practices in Introductions: Phraseology and Semantic Sequences across Genres
NJES: Nordic Journal of English studies, 2010 The study of metadiscursive practices is particularly fruitful in introductory part-genres where the representation of disciplinary discursive procedures plays a major role for the discourse community.
Marina Bondi
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Journal of Language and LiteratureThis research aimed at finding the interpersonal metadiscourse markers in Joe Biden’s speech remarks on Bidenomics 2023. The researchers also attempted to comprehend in depth the context of interpersonal metadiscourse markers through discourse analysis ...
Andina Silvi Amalia, Rina Sari
doaj +1 more source