Results 91 to 100 of about 17,556 (227)

Environmental heterogeneity and spatial variation mediates plant diversity and ecosystem stability in mountain ecosystems of the Mediterranean Andes

open access: yesEcography, EarlyView.
Globally, mountains are highly diverse ecosystems that serve as natural laboratories for testing ecological theories, while providing vital ecosystem services. Their biodiversity arises from the interaction between elevational gradients and topographic complexity, which generate strong variation in environmental conditions across short spatial scales ...
Laura C. Pérez‐Giraldo   +3 more
wiley   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu   +3 more
wiley   +1 more source

Do Institutions Make Street‐Level Bureaucrats Prosocial? Agent‐Based Evidence Shows That New Public Management Does Not

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT Does street‐level bureaucrats' (SLBs) willingness to sacrifice their own self‐interests to meet the needs of their clients vary depending on their contexts? To date, it has been very challenging to empirically examine how SLBs who have different orientations toward social values might act in different institutional and administrative contexts.
Nissim Cohen, Teddy Lazebnik
wiley   +1 more source

Altered neurostructural development in magnetic resonance imaging‐negative pediatric epilepsy: A large‐scale multicenter study of 1919 children

open access: yesEpilepsia, EarlyView.
Abstract Objective Addressing the poorly understood impact of pediatric epilepsy on neurodevelopment, this large‐scale study delineates age‐ and sex‐stratified neurostructural trajectories in magnetic resonance imaging (MRI)‐negative pediatric epilepsy to identify periods of maximal developmental divergence from healthy controls.
Yingfan Wang   +10 more
wiley   +1 more source

Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan   +23 more
wiley   +1 more source

Inroads into epilepsy through high‐frequency oscillations: Achievements and benchmark areas for improvement

open access: yesEpilepsia, EarlyView.
Abstract High‐frequency oscillations (HFOs) were discovered more than 20 years ago, and since then they have been studied intensively in the context of epilepsy. HFOs encompass a broad spectrum of oscillations, typically ranging from 80 Hz to several kHz, that include both normal and pathological oscillations, documented in people with epilepsy and ...
Christos Panagiotis Lisgaras   +6 more
wiley   +1 more source

Characterizing early behavioral and social–emotional problems in young children with SCN1A+ Dravet syndrome: Findings from the ENVISION prospective natural history study

open access: yesEpilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is the prototypic developmental and epileptic encephalopathy, characterized by drug‐resistant seizures, developmental slowing, and many other morbidities. Detailed characterization of behavioral phenotypes and social–emotional skill development are limited.
Ingrid E. Scheffer   +26 more
wiley   +1 more source

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