Results 81 to 90 of about 3,879 (212)

Inroads into epilepsy through high‐frequency oscillations: Achievements and benchmark areas for improvement

open access: yesEpilepsia, EarlyView.
Abstract High‐frequency oscillations (HFOs) were discovered more than 20 years ago, and since then they have been studied intensively in the context of epilepsy. HFOs encompass a broad spectrum of oscillations, typically ranging from 80 Hz to several kHz, that include both normal and pathological oscillations, documented in people with epilepsy and ...
Christos Panagiotis Lisgaras   +6 more
wiley   +1 more source

Characterizing early behavioral and social–emotional problems in young children with SCN1A+ Dravet syndrome: Findings from the ENVISION prospective natural history study

open access: yesEpilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is the prototypic developmental and epileptic encephalopathy, characterized by drug‐resistant seizures, developmental slowing, and many other morbidities. Detailed characterization of behavioral phenotypes and social–emotional skill development are limited.
Ingrid E. Scheffer   +26 more
wiley   +1 more source

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan   +20 more
wiley   +1 more source

The normalizing properties of intracranial volume across race and sex. [PDF]

open access: yesBrain Commun
Liu P   +14 more
europepmc   +1 more source

Fenfluramine in SCN1A‐related GEFS+: A multicenter observational study on efficacy, EEG improvement, and tolerability

open access: yesEpilepsia Open, EarlyView.
Abstract The SCN1A gene is implicated in a broad spectrum of epilepsy phenotypes, ranging from self‐limited genetic epilepsy with febrile seizures plus (GEFS+) to severe developmental and epileptic encephalopathies such as Dravet syndrome (DS). While fenfluramine (FFA) has demonstrated strong efficacy in DS, its role in SCN1A‐related epilepsies beyond ...
Giovanni B. Dell'Isola   +12 more
wiley   +1 more source

How to report neurotechnology and artificial intelligence studies in epilepsy: Peer‐review‐inspired recommendations

open access: yesEpilepsia Open, EarlyView.
Abstract Objective The integration of neurotechnology and artificial intelligence (AI) in epilepsy research has led to significant advancements in diagnosis, monitoring, and treatment. However, the impact of these innovations is often diminished by inadequate and inaccurate reporting, limiting their reproducibility and implementation.
Pedro F. Viana   +6 more
wiley   +1 more source

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