Results 101 to 110 of about 8,265,161 (304)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Ripening and Focusing of Aggregate Size Distributions with Overall Volume Growth
Frontiers in Physics, 2014 We explore the evolution of the aggregate size distribution in systems where aggregates grow by diffusive accretion of mass. Supersaturation is controlled in such a way that the overall aggregate volume grows linearly in time. Classical Ostwald ripening,
Jürgen eVollmer +5 more
doaj +1 more source
Information and Self-Organization
Entropy, 2016 The process of “self-organization” takes place in open and complex systems that acquire spatio-temporal or functional structures without specific ordering instructions from the outside. [...]
H. Haken, J. Portugali
semanticscholar +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Topological phase locking in stochastic oscillators
Nature CommunicationsThe dynamics of many nanoscale biological and synthetic systems such as enzymes and molecular motors are activated by thermal noise, and driven out-of-equilibrium by local energy dissipation.
Michalis Chatzittofi +2 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Embodied cognition through cultural interaction [PDF]
, 2004 In this short paper we describe a robotic setup to study the self-organization of conceptualisation and language. What distinguishes this project from others is that we envision a robot with specic cognitive capacities, but without resorting to any pre ...
Belpaeme, Tony +2 more
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Democratic Reinforcement: Learning via Self-Organization
, 1995 The problem of learning in the absence of external intelligence is discussed in the context of a simple model. The model consists of a set of randomly connected, or layered integrate-and fire neurons.
Bak, Per, Stassinopoulos, Dimitris
core +1 more source