Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
In-Line Enrichment of Cancer Cells from Whole Blood by Cell Self-Organization in Acoustic Fields. [PDF]
Anal ChemSoller R, Jakobsson O, Augustsson P.
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Advanced Healthcare Materials, EarlyView.Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez +6 more
wiley +1 more source
Corrigendum to "Intrinsic clustering of flagellar basal body proteins in <i>E. coli</i>: A self-organization mechanism for assembly and regulation" Biochem. Biophys. Reports 42 (2025) 102051. [PDF]
Biochem Biophys RepSung YS, Hong DF, Chang YR.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni +7 more
wiley +1 more source
Self-organization of sinusoidal vessels in pluripotent stem cell-derived human liver bud organoids. [PDF]
Nat Biomed EngSaiki N +16 more
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Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing
Advanced Healthcare Materials, EarlyView.We report a thermally triggered supramolecular hydrogel (LTFe) formed by Fe3+ and tannic acid on lysozyme amyloid fibrils. Fe3+ enables rapid gelation and photothermal transduction with an efficiency of 88.56%. The LTFe hydrogel exhibits excellent biocompatibility, potent antibacterial activity against E. coli and S.
Di Wu +8 more
wiley +1 more source
Patterning the Pore Orientation of Nanoporous Metal via Self-Organization in Flow Cells. [PDF]
Adv Sci (Weinh)Wang C, Li Y, Geng X, Mao J, Chen Q.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Spontaneous helical alignment of smooth muscle cells is induced within resistance‐vessel‐sized channels patterned within a hydrogel. The extent of the cells’ orientation angle is dependent on the presence and composition of ECM proteins lining the channel wall and cell seeding density.
Victoria D. Vest +5 more
wiley +1 more source
Kinetic Theory with Casimir Invariants-Toward Understanding of Self-Organization by Topological Constraints. [PDF]
Entropy (Basel)Yoshida Z.
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