Results 151 to 160 of about 90,302 (257)

Phenome-wide association study identifies multiple traits associated with a polygenic risk score for colorectal cancer. [PDF]

Hum Genomics
Rosenthal EA, Wei WQ, Luo Y, Namjou-Khales B, Schaid DJ, Esplin ED, Lape M, Kottyan L, Pacheco JA, Weng C, Gordon AS, Kullo IJ, Crosslin DR, Grady WM, Hsu L, Peters U, Jarvik GP.   +16 more
europepmc   +1 more source

Real‐Time, Label‐Free Classification of Cell Death Pathways via Holotomography‐Based Deep Learning Framework

Advanced Intelligent Systems, EarlyView.
A 3D holotomography system coupled with a deep learning model distinguishes how cells die—apoptosis, necroptosis or necrosis—without any fluorescent labels. Training on refractive index maps of HeLa cells yields 97% accuracy and flags necroptosis hours before chemical dyes.
Minwook Kim, Wei Sun Park, Geon Kim, Sanggeun Oh, Jaephil Do, Juyeon Park, Jihwan Yu, Won Do Heo, YongKeun Park   +8 more
wiley   +1 more source

Conservative port-to-port funneling of light in nonlinear photonic lattices. [PDF]

Nat Commun
Pyrialakos GG, Dinani HM, Jeon DH, Nazarlu MG, Ren H, Berman Bradley AM, Khajavikhan M, Christodoulides DN.   +7 more
europepmc   +1 more source

Bridging High‐Fidelity Simulations and Physics‐Based Learning using a Surrogate Model for Soft Robot Control

Advanced Intelligent Systems, EarlyView.
A surrogate‐model‐based framework is proposed for combining high‐fidelity finite element method and efficient physics simulations to enable fast, accurate soft robot simulation for reinforcement learning, validated through sim‐to‐real experiments. Soft robotics holds immense promise for applications requiring adaptability and compliant interactions ...
Taehwa Hong, Jungjae Lee, Byung‐Hyun Song, Yong‐Lae Park   +3 more
wiley   +1 more source

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

Angewandte Chemie, EarlyView.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +2 more sources

A foundation model for rock thin-section images analysis. [PDF]

Commun Eng
Fan J, Yu X, Di Y, Lv T, Zhang R, Bao J, Liu Y, Li L, Pan X.   +8 more
europepmc   +1 more source

Degeneracy Sensing Light Detection and Ranging‐Inertial Simultaneous Localization and Mapping with Dual‐Layer Resistant Odometry and Scan‐Context Loop‐Closure Detection Backend in Diverse Environments

Advanced Intelligent Systems, EarlyView.
This paper presents a degeneracy‐aware light detection and ranging (LiDAR)‐inertial framework that enhances LiDAR simultaneous localization and mapping performance in challenging environments. The proposed system integrates a dual‐layer robust odometry frontend with a Scan‐Context‐based loop‐closure detection backend.
Haoming Yang, Liye Zhao, Xukai Ding, Wenjun Li, Kehao Qi   +4 more
wiley   +1 more source

Self-rated health, mental wellbeing, nutrition habits, and their association with morbidity of ischemic heart disease. [PDF]

Front Public Health
Aukstakalniene G, Luksiene D, Tamosiunas A, Sileikiene L, Lesauskaite V.   +4 more
europepmc   +1 more source

Review of Memristors for In‐Memory Computing and Spiking Neural Networks

Advanced Intelligent Systems, EarlyView.
Memristors uniquely enable energy‐efficient, brain‐inspired computing by acting as both memory and synaptic elements. This review highlights their physical mechanisms, integration in crossbar arrays, and role in spiking neural networks. Key challenges, including variability, relaxation, and stochastic switching, are discussed, alongside emerging ...
Mostafa Shooshtari, Teresa Serrano‐Gotarredona, Bernabé Linares‐Barranco   +2 more
wiley   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, EarlyView.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +2 more sources