Results 111 to 120 of about 6,509,197 (268)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Material and Administrative Components of Financial Toxicity and Survivorship Well‐Being: A Cross‐Sectional Analysis of HINTS (2012–2017)

Cancer Medicine
Background Financial toxicity is a multidimensional construct shaped by material, psychological, and administrative pressures. This study examines how two components, namely, material burden and a narrow administrative indicator (insurance denial), are ...
Ivan H. C. Wu, Samuel R. Harris, Rachel Price, Shikha Bista   +3 more
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Multifaceted self-concept of indigenous Australian secondary students : structure and relations to other academic variables

, 2006
In response to recent calls for the development of culturally relevant and applicable quantitative instruments for research into the educational disadvantages suffered by Indigenous Australian students, Bodkin-Andrews, Craven & Marsh (2005) analysed the ...
Craven, Rhonda, Bodkin-Andrews, Gawaian
core  

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Self-perceived cause of pain.

, 2018
Self-perceived cause of pain.
Siu Wai Choi (751151), Chi Wai Cheung (614393), Stanley Sau Ching Wong (2271274)   +2 more
core   +1 more source

Latent profile analysis and influencing factors of self-perceived burden in patients after surgery for anal fistula (肛瘘术后患者自我感受负担的潜在剖面分析与影响因素研究)

中西医结合护理
Objective This study aimed to explore the latent categories and influencing factors of self-perceived burden in patients after anal fistula surgery. Methods Using a convenience sampling method, postoperative patients undergoing surgery for anal fistula
XU Zhaojun (徐召君), ZHANG Shuixia (张水夏), PAN Yajun (潘亚君), HE Sixin (何思欣), LUO Linghua (罗玲花), WANG Miaolan (王淼兰), CHEN Piao (陈飘)   +6 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

The relationship between self-perceived burden, depression, medication adherence, and health-related quality of life in coronary heart disease patients

, 2017
The feeling of being a burden to others, also known as self-perceived burden, is an understudied construct among patients with chronic illnesses, despite its numerous potentially detrimental consequences on the patient’s health and well-being.
Lim, Benjamin Chee Chong
core  

[Family caregiver's self-perceived health status and its relation to burden].

Psicothema, 2011
The study aims to analyze how health is self-perceived by a sample of caregivers of dependant relatives and how it compares with general Spanish population scores. The study also focuses on the relations between self-perceived health and burden. The sample comprised 1,257 caregivers living in Biscay who completed the protocol including sociodemographic
Pedro, Fernández de Larrinoa Palacios, Silvia, Martínez Rodríguez, Nuria, Ortiz Marqués, María, Carrasco Zabaleta, Josu, Solabarrieta Eizaguirre, Ignacio, Gómez Marroquín   +5 more
openaire   +1 more source