Results 141 to 150 of about 7,144,096 (336)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Self supervised learning based emotion recognition using physiological signals

Frontiers in Human Neuroscience
IntroductionThe significant role of emotional recognition in the field of human-machine interaction has garnered the attention of many researchers. Emotion recognition based on physiological signals can objectively reflect the most authentic emotional ...
Min Zhang, YanLi Cui
doaj   +1 more source

Feel the beat: using cross-modal rhythm to integrate perception of objects, others, and self [PDF]

, 2004
For a robot to be capable of development, it must be able to explore its environment and learn from its experiences. It must find (or create) opportunities to experience the unfamiliar in ways that reveal properties valid beyond the immediate context. In
Arsenio, Artur, Fitzpatrick, Paul
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

A statistical mechanics approach to autopoietic immune networks

, 2010
The aim of this work is to try to bridge over theoretical immunology and disordered statistical mechanics. Our long term hope is to contribute to the development of a quantitative theoretical immunology from which practical applications may stem.
Abbas A K, Adriano Barra, Agliari E, Amit D J, Barra A, Burnet F M, Burnet F M, Celada F, Coolen A C C, Delves P, Dreyer W J, Edelman G M, Elena Agliari, Ellis R S, Elrich P, Farmer J D, Jerne N K, Ledemberg J, Mandl F, Nesterenko V G, Newman M, Rose N R, Seigneurin J M, Semerjian G, Varela F J   +24 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Ruskin, Reflection, Self recognition and Self creation in Proust [PDF]

, 2010
Tribout-Joseph, Sarah
core   +1 more source

Neo-Thomism and the Problem of Animal Suffering [PDF]

, 2019
Proponents of the problem of animal suffering claim that the millions of years of apparent nonhuman animal pain and suffering provides evidence against the existence of God.
Keltz, B. Kyle
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Islamic Virtues in The Javanese Muslim Tradition: A Philosophical Investigation on Damardjati Supadjar’s Religious Ethics

Ijtimā'iyya, 2016
Since firstly transmitted in Java and became a major religion, about 700 years agoor even more, Islam has met with many older cultures and traditions that had been existed hundreds of years before, and grew so far with numerous model of synthesises ...
M. Nur Prabowo Setyabudi
doaj