Results 91 to 100 of about 1,310,252 (335)

Longitudinal Intergroup Contact Effects on Prejudice Using Self- and Observer-Reports [PDF]

open access: yes, 2012
Longitudinal effects of intergroup contact on prejudice were investigated in a sample of 65 young adults (Sample 1) and a sample of their close friends (Sample 2, N = 172), adopting a full cross-lagged panel design.
Allemand   +46 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

How many people use alternative media in Germany and how can we measure it?

open access: yesJournal of Quantitative Description: Digital Media
Digital media are often assumed to facilitate the production and spread of alternative news outlets. So far, however, it is quite unclear whether exposure to alternative media is a mass or a niche phenomenon. Although several studies attempted to measure
Tilman Klawier
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

The Effect of Education on Crime: Evidence from Prison Inmates, Arrests, and Self-Reports [PDF]

open access: yes
We estimate the effect of high school graduation on participation in criminal activity accounting for endogeneity of schooling. We begin by analyzing the effect of high school graduation on incarceration using Census data. Instrumental variable estimates
Enrico Moretti, Lance Lochner
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

The Role of Motivational Persistence and Resilience Over the Well-being Changes Registered in Time [PDF]

open access: yes, 2015
The present study investigates the interaction between personal characteristics that are considered nowadays strengths used to face difficult events or transition period.
Bostan, Cristina Maria
core  

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