Results 81 to 90 of about 6,285,668 (303)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
The relation of self-concept to desirable educational outcomes
Reviewers (Byrne, 1996a, 1996b; Hattie, 1992; Marsh, Byrne, & Shavelson, 1988; Marsh & Craven, 1997; Craven, Marsh, & Burnett, 2003) consider that self-concept is multifaceted and espouse that self-concept cannot be adequately understood if its ...
Craven, Rhonda +3 more
core
‘It is a pity that not someone like Christina Leonora de Neufville found the time to take on that work’, translator and author Elizabeth Wolff stated when she set eyes on one of the Dutch translations of Voltaire’s Mahomet (1741) in October 1770.
Lieke van Deinsen, Beatrijs Vanacker
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Political strategies of self-representation: The case of young Afghan migrants in Sweden
In this chapter I explore how children and youth make use of particular strategies of self-representation to seek political representation. I do so by taking my point of departure in a group of young Afghan migrants in Sweden and their political ...
Josefsson, Jonathan
core +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The significance of the linguistic representation of self in research
A linguistic framework for the analysis of self was constructed to enable understanding of the participant's view. This linguistic framework has been elucidated in this chapter to consider the significance the linguistic representations of self has on ...
Salton, Yvonne
core +1 more source
Représentations auctoriales dans Excel Saga : figures, enjeux et métafiction
In Japan, the Excel Saga anime exhibits a self-portrayal of the particular and exuberant author. Indeed, in the context of an animated series, linked to the modalities of popular culture, self-representation is not limited to the author of the original ...
Sofiane Taouchichet
doaj
Palestinian Dynamics of Self-Representation:
This paper deals with the dialectics of identity construction and self-representation in the Palestinian national movement. It demonstrates how some transformations regarding self-image have been transpiring among Palestinians. It is divided into two main parts: the first deals with the first three decades following the 1948 exile during which ...
openaire +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source

