Results 201 to 210 of about 549,786 (309)

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

Advanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai, Zhuoying Huang, Haonan Lin, Guangrui Ding, Hongjian He, Menna Siddiqui, Meng Zhang, Wilson Wong, Ji‐Xin Cheng   +8 more
wiley   +1 more source

A self-supervised learning method for detection of retinitis pigmentosa and Stargardt disease. [PDF]

Sci Rep
Karimi A, Ahmadieh H, Sadeghi Tabrizi M, Daftarian N, Farshian Abbasi A, Fekri S, Ghattan Kashani H, Baghban Jaldian H, Yazdanpanah M, Shariat Panahi M, Sabbaghi H.   +10 more
europepmc   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Denoising self-supervised learning for disease-gene association prediction. [PDF]

BMC Bioinformatics
Zhang Y, Xiang J, Li J.
europepmc   +1 more source

Direct Recycling of Mixed‐Oxide Cathodes: Balancing Cost, Performance and Environmental Trade‐Offs

Advanced Science, EarlyView.
Direct regeneration routes for mixed‐oxide lithium‐ion battery cathodes are systematically compared using harmonized techno‐economic, electrochemical, and environmental metrics. Solid‐state, hydrothermal, molten salt, electrochemical, and chemical relithiation methods are benchmarked to identify performance, cost, and sustainability trade‐offs.
Evgenii Beletskii, Elizaveta Evshchik, Anna Shikhovtseva, Valery Kolmakov, Andrey Popov, Svetlana Eliseeva, Lyubov Shmygleva, Yurii K. Gun'ko, Valentin Romanovski   +8 more
wiley   +1 more source

Lightweight self supervised learning framework for domain generalization in histopathology. [PDF]

Sci Rep
Shafique A, Dy A, Qin X, Alshamlan N, Androutsos D, Done SJ, Khademi A.   +6 more
europepmc   +1 more source

vEMRec: High‐Resolution Volume Electron Microscopy Reconstruction Based on Structure‐Preserving and High‐Fidelity 3D Alignment

Advanced Science, EarlyView.
vEMRec is a frequency‐adaptive computational framework for three‐dimensional alignment in volume electron microscopy. It integrates feature‐based rigid alignment with Gaussian filter‐guided elastic registration to correct rigid misalignments and nonlinear distortions while preserving structural fidelity.
Zhenbang Zhang, Hongjia Li, Zhongjun Yang, Zhiqiang Xu, Duanchen Sun, Xin Gao, Fa Zhang, Renmin Han   +7 more
wiley   +1 more source

Paft-wpest: wolfberry pests fine-grained classification method based on generative self-supervised learning. [PDF]

Plant Methods
Liu J, Zhang Y, Zhang J, Wang J, Zhou G, Sun W, Liu L, Ren H, Chen X, Liu P.   +9 more
europepmc   +1 more source

Every Node Counts: Self-Ensembling Graph Convolutional Networks for Semi-Supervised Learning [PDF]

, 2018
Yawei Luo, Tao Guan, Junqing Yu, Ping Liu, Yi Yang   +4 more
openalex   +1 more source

Self-supervised learning for clustering of wireless spectrum activity

, 2023
Ljupcho Milosheski, Gregor Cerar, Blaž Bertalanič, Carolina Fortuna, Mihael Mohorčič   +4 more
openalex   +1 more source