Results 211 to 220 of about 546,017 (306)

NanoSSL: attention mechanism-based self-supervised learning method for protein identification using nanopores. [PDF]

open access: yesBioinformatics
Xie Y   +9 more
europepmc   +1 more source

Mapping Charge Interactions in Intrinsically Disordered Proteins

open access: yesAdvanced Science, EarlyView.
This study presents analytical models to predict intrachain distances in intrinsically disordered proteins (IDPs), accounting for charge patterning, salt concentration, and electrostatic effects. Validated against single‐molecule FRET data, a minimal‐parameter polymer model is identified that captures key interactions and chain dimensions. These models
Michael Phillips   +14 more
wiley   +1 more source

A generalizable 3D framework and model for self-supervised learning in medical imaging. [PDF]

open access: yesNPJ Digit Med
Xu T   +6 more
europepmc   +1 more source

Genetic underpinnings of predicted changes in cardiovascular function using self supervised learning [PDF]

open access: gold
Zachary Levine   +8 more
openalex   +1 more source

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

open access: yesAdvanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li   +8 more
wiley   +1 more source

Self-supervised learning to predict intrahepatic cholangiocarcinoma transcriptomic classes on routine histology. [PDF]

open access: yesJHEP Rep
Beaufrère A   +16 more
europepmc   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang   +10 more
wiley   +1 more source

Stretchable Curvature Sensors for Motion Capture with Bending‐Stretching Coupling Deformation

open access: yesAdvanced Science, EarlyView.
Stretchable curvature sensors based on a wavy symmetric stacked‐layer structure (WSSLS) enable decoupled bending‐stretching detection with high linearity, repeatability, and durability. Integrated into smart gloves, the sensors achieved precise motion capture and human‐robot interaction, with slip‐simulation tests demonstrating a remarkable 93.6 ...
Tairan Wang   +9 more
wiley   +1 more source

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