Results 241 to 250 of about 546,017 (306)

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

open access: yesAdvanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou   +14 more
wiley   +1 more source

EVA-X: a foundation model for general chest x-ray analysis with self-supervised learning. [PDF]

open access: yesNPJ Digit Med
Yao J   +7 more
europepmc   +1 more source

Sulfate‐Directed Silver Dendrites with Enhanced Stability for Ultrasensitive SERS‐Based Therapeutic Drug Monitoring

open access: yesAdvanced Science, EarlyView.
This study presents sulfate‐directed silver dendrites (s‐AgDs) as oxidation‐resistant SERS substrates with long‐term stability, reproducibility, and sub‐picomolar sensitivity. Sulfate ions guide anisotropic growth and protect the surface, enabling improved performance over 7 months under ambient conditions.
Aradhana Dwivedi   +6 more
wiley   +1 more source

A foundation transformer model with self-supervised learning for ECG-based assessment of cardiac and coronary function. [PDF]

open access: yesNEJM AI
Moody JB   +9 more
europepmc   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

open access: yesAdvanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang   +12 more
wiley   +1 more source

Privacy-Aware Continual Self-Supervised Learning on Multi-Window Chest Computed Tomography for Domain-Shift Robustness. [PDF]

open access: yesBioengineering (Basel)
Tasai R   +11 more
europepmc   +1 more source

Spectral Decomposition of Chemical Semantics for Activity Cliffs‐Aware Molecular Property Prediction

open access: yesAdvanced Science, EarlyView.
PrismNet mimics chemical intuition by functioning as a computational prism, refracting molecular graphs into complementary semantic views and spectral frequencies. This dual‐decomposition strategy effectively captures both global topologies and subtle “activity cliff” perturbations.
Chaoyang Xie   +9 more
wiley   +1 more source

Leveraging unlabeled SEM datasets with self-supervised learning for enhanced particle segmentation. [PDF]

open access: yesNPJ Comput Mater
Rettenberger L   +7 more
europepmc   +1 more source

Dual Bipolar Resistive Switching in Wafer‐Scalable 2D Perovskite Oxide Nanosheets‐Based Memristor

open access: yesAdvanced Science, EarlyView.
A wafer‐scalable memristor based on 2D Sr2Nb3O₁₀ perovskite oxide nanosheets exhibits dual bipolar resistive switching through controllable oxygen ion migration and redox reactions. This single device enables both STDP and anti‐STDP synaptic functions, achieving 86.4% MNIST accuracy in supervised spiking neural networks, offering a compact, energy ...
Sohwi Kim   +11 more
wiley   +1 more source

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