Results 81 to 90 of about 14,971 (268)

The role of GABAB receptors in morphine self-administration

International Journal of Preventive Medicine, 2013
Background: There is only little information about the effects of GABA receptors agonist and antagonist on morphine self-administration. Present study was designed to assess role of GABAB receptors in the regulation of morphine-reinforced self ...
Effat Ramshini, Hojjatallah Alaei, Parham Reisi, Samaneh Alaei, Somaye Shahidani   +4 more
doaj  

Cocaine Self-administration and Extinction Inversely Alter Neuron to Glia Exosomal Dynamics in the Nucleus Accumbens [PDF]

, 2020
Rachel Jarvis, Alessandra Tamashiro Orrego, Vanessa Promes, Leona Tu, Jinyuan Shi, Yongjie Yang   +5 more
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Systematic literature review of asthma biologic self-administration enhanced by a patient perspective

Journal of Allergy and Clinical Immunology: Global
Background: Several biologics for the treatment of severe asthma are available as self-administration devices. Objective: We performed a systematic literature review to understand the use, benefits, and challenges of these self-administration devices ...
Simona Boccaletti, MSc, Rafael Alfonso-Cristancho, PhD, Waseem Ahmed, MBA, Lehanne Sergison, Adaeze Eze, MSc, Prashant Auti, MS (Pharm), Cathelijne Alleman, MSc, Lohit Badgujar, PhD, Nicholas Halfpenny, MSc, Dorothea Heldt, MSc   +9 more
doaj   +1 more source

Differential Effects of Presynaptic versus Postsynaptic Adenosine A_2AReceptor Blockade on Δ⁹-Tetrahydrocannabinol (THC) Self-Administration in Squirrel Monkeys [PDF]

, 2014
Zuzana Justinová, Godfrey H. Redhi, Steven R. Goldberg, Sergi Ferré   +3 more
openalex   +1 more source

ADDICTION-LIKE BEHAVIOR INDUCED BY SATURATED AND UNSATURATED FAT-ENRICHED DIETS IN AN ANIMAL MODEL OF OPERANT SELF-ADMINISTRATION [PDF]

, 2023
M. Roca, Ana Belén Sanz Martos, Yunes Mohamedi Ahmed, Emilio Ambrosio, Nuria Del Olmo   +4 more
openalex   +1 more source

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Nephrocalcinosis fortuitously discovered: the role of surreptitious self administration of diuretics [PDF]

Caspian Journal of Internal Medicine
Background: Furosemide is a drug widely used for several medical conditions and could be used without medical prescription. Furosemide-related nephrocalcinosis can occur regardless of age, although the risk is higher in premature infants.
Nery Sablon Gonzalez, Liliana Moran Caicedo, Maria Belen Alonso Ortiz, Yanet Parodis Lopez, Angelica Laurin, Emmanuel Andrès, Noel Lorenzo Villalba   +6 more
doaj  

Lack of effect of different pain-related manipulations on opioid self-administration, reinstatement of opioid seeking, and opioid choice in rats [PDF]

, 2021
David J. Reiner, E. Andrew Townsend, Javier Orihuel Menendez, Sarah V. Applebey, Sarah M. Claypool, Matthew L. Banks, Yavin Shaham, S. Stevens Negus   +7 more
openalex   +1 more source