Results 31 to 40 of about 844,415 (256)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relationship of Self Efficacy with Self Care Management in Hypertension Patients

Journal of Pubnursing Sciences
Latar Belakang: Efikasi diri pada pasien hipertensi sangat penting untuk meningkatkan rasa percaya diri mereka dalam melakukan manajemen perawatan diri, sehingga dapat mencegah peningkatan morbiditas, mortalitas, dan komplikasi yang timbul akibat ...
Berlian Maharani Febrina Putri, Moh. Ubaidillah Faqih   +1 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The status of academic self-efficacy in the students of Kurdistan University of Medical Sciences and Islamic Azad University, Sanandaj Branch, 2015-16.

فصلنامه پرستاری،مامایی و پیراپزشکی, 2017
Background & Aim: Educational self-efficacy implies a person's belief in his or her abilities in achieving educational goals and activities, the formation of which is influenced by various factors.
Boshra Vahabi, Ahmad Vahabi, Sirvan Sayyad, Mahnaz Sayyadi, Daem Roshani, Shahnaz Hajisahne   +5 more
doaj  

Relationship Between Self Efficacy And Self Regulation In Diabetes Mellitus Patients

Professional Health Journal
Diabetes Mellitus is an incurable disease that affects aspects of life and increases the risk of complications that can cause death. Complications can be minimized if the patient has compliance, knowledge, and ability to perform self-care .
Devi Setya Putri, Alvina Setiani, Luluk Cahyanti   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Self Regulated Learning dan Self Efficacy Mahasiswa Tim Debat Bahasa Arab al-Kindy

Arabiyatuna: Jurnal Bahasa Arab, 2019
The skill of speaking Arabic is a demand in the campus world and after graduation as a form of readiness to enter the workforce in the global era. Teaching kalam with the debate method for students besides being able to improve ability also adds courage ...
Nuril Mufidah, Warisma Riski Nuryani
doaj   +1 more source

THE CONCEPT OF SELF-EFFICACY AND SELF-EFFICACY-PERFORMANCE RELATIONSHIP

Ankara Üniversitesi SBF Dergisi, 2000
Self-Efficacy (SE) is the belief or perception of a pcrson that he or she is capable to perform a specific task. It is a dynamic element that influenccs other concepts such as goals, performance and is influenced by them. SE is an essential element in Social Cognitive Learning Theory.
openaire   +3 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source