Results 71 to 80 of about 16,352,862 (306)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Self-Augmented Noisy Image for Noise2Noise Image Denoising

open access: yesIEEE Access
Image denoising is a critical task in image processing aimed at removing noise artifacts. Typically, supervised deep learning often necessitates a large number of pairs of noisy and noise-free images for training. Noise2Noise techniques have demonstrated
Asavaron Limsuebchuea   +2 more
doaj   +1 more source

Choosing face: The curse of self in profile image selection

open access: yesCognitive Research, 2017
People draw automatic social inferences from photos of unfamiliar faces and these first impressions are associated with important real-world outcomes. Here we examine the effect of selecting online profile images on first impressions.
David White   +2 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Video and image processing with self-organizing neural networks

open access: yes, 2011
This paper aims to address the ability of self-organizing neural network models to manage video and image processing in real-time. The Growing Neural Gas networks (GNG) with its attributes of growth, flexibility, rapid adaptation, and excellent quality ...
García-Rodríguez, J.   +6 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

A correlational study to assess the relationship between body image, appearance contingent self-worth, and self-compassion among youth of Karnataka

open access: yesClinical Epidemiology and Global Health
Background: Body-image is defined as “a stable, complex, mental representation of our body and its emotional experience”. Negative perception concerning one's own body is associated with several mental disorders like stress related to the body, binge ...
Preejana Sharma   +2 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Self-beliefs and bullying : unravelling the relation between bullying, being bullied and self-concept for upper elementary school aged children

open access: yes, 2006
Previous examinations of relations between bullying, victimisation, and self-concept have been flawed by erroneous research practices such as the un-attenuated use of dichotomous variables to measure relationships between continuous variables (Finger ...
Finger, Linda R.   +2 more
core  

Brand Image as a Function of Self-Image and Self-Brand Connection

open access: yesManagement Dynamics in the Knowledge Economy, 2014
This study investigates how brand image relates to self-image and how brand consumption contributes to the construction of self. Most of the research on brand image refers to brand attitudes. Day (1970) considers attitudes "a central integrating feature”
Rares MOCANU
doaj  

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