Results 61 to 70 of about 2,780,213 (277)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Children and Adults Prefer the Egocentric Representation to the Allocentric Representation

Frontiers in Psychology, 2018
We studied the strategy preference of using the egocentric or the allocentric representation in individuals who have acquired the ability to use both representations.
Qingfen Hu, Ying Yang, Zhenzhen Huang, Yi Shao   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Site-bond representation and self-duality for totalistic probabilistic cellular automata

, 2005
We study the one-dimensional two-state totalistic probabilistic cellular automata (TPCA) having an absorbing state with long-range interactions, which can be considered as a natural extension of the Domany-Kinzel model.
Atman A P F, Bagnoli F, Durrett R, Konno N, Liggett T M, Liggett T M, López F J, N Konno, Sudbury A W, Wolfram S, X Ma   +10 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Closed Strings with Low Harmonics and Kinks

, 1993
Low-harmonic formulas for closed relativistic strings are given. General parametrizations are presented for the addition of second- and third-harmonic waves to the fundamental wave.
A. Albrecht, A. Cresswell, A. Polnarev, A. Vilenkin, A. Vilenkin, A. Vilenkin, A.L. Chen, B. Allen, B. Allen, C. Thompson, C.J. Burden, D. Garfinkle, D. Hochberg, D.B. Delaney, E.J. Copeland, E.P.S. Shellard, F. Embacher, F. Embacher, F. Embacher, J. Garriga, J.M. Quashnock, L. Perivolaropoulos, L. S. Petropoulos, M. Aryal, M. E. Convery, M. G. Knepley, N. Turok, N. Turok, N. Turok, P. Amsterdamski, P. Goddard, P. Laguna, R. Durrer, R. W. Brown, R.A. Matzner, R.J. Scherrer, R.J. Scherrer, R.W. Brown, R.W. Brown, R.W. Brown, R.W. Brown, S. A. Hotes, T. Vachaspati, T. York, T.W.B. Kibble, T.W.B. Kibble, W. Press   +46 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A minimal representation of the self-assembly of virus capsids

, 2013
Viruses are biological nanosystems with a capsid of protein-made capsomer units that encloses and protects the genetic material responsible for their replication.
Breton, J., Hernandez-Rojas, J., Llorente, J. M. Gomez   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source