Results 101 to 110 of about 28,779 (287)

Self-Knowledge and Self-Love [PDF]

open access: yesEthical Theory and Moral Practice, 2015
In this paper I argue for the claim that self-love is a precondition for self-knowledge. This claim is relevant to the contemporary philosophical debate on self-knowledge, but mainly because it draws attention to the role of claims of self-knowledge in the larger context of our ordinary practice of rationalizing and appropriating our actions.
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Genome-wide patterns of segregation and linkage disequilibrium: the construction of a linkage genetic map of the poplar rust fungus Melampsora larici-populina

open access: yesFrontiers in Plant Science, 2014
The poplar rust fungus Melampsora larici-populina causes significant yield reduction and severe economic losses in commercial poplar plantations. After several decades of breeding for qualitative resistance and subsequent breakdown of the released ...
Michael ePernaci   +6 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Breeding system and pollination of Pleroma trichopodum DC. (Melastomataceae): a potential species for the restoration of Atlantic Forest in southern Brazil

open access: yesActa Botânica Brasílica, 2018
Plant-pollinator interactions and their reproductive implications are of central importance to the organization of plant populations and communities in restoration areas.
Tiago Simões Malucelli   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Multiple aspects of the selfing syndrome of the morning glory Ipomoea lacunosa evolved in response to selection: A Qst‐Fst comparison

open access: yesEcology and Evolution, 2019
The frequent transition from outcrossing to selfing in flowering plants is often accompanied by changes in multiple aspects of floral morphology, termed the “selfing syndrome.” While the repeated evolution of these changes suggests a role for natural ...
Joanna L. Rifkin   +3 more
doaj   +1 more source

The breeding system and effectiveness of introduced and native pollinators of the endangered tropical tree Goetzea elegans (Solanaceae)

open access: yesJournal of Pollination Ecology, 2011
The impact of introduced species on native organisms is one of the main conservation concerns around the world. To fully understand the effect of introduced pollinators on native plants, it is important to know the reproductive biology of the focal ...
Marcos A. Caraballo-Ortiz   +1 more
doaj   +1 more source

Individual Self, Relational Self, Collective Self: Hierarchical Ordering of the Tripartite Self

open access: yesPsychological Studies, 2011
The individual self comprise unique attributes, the relational self comprises partner-shared attributes, and the collective self comprises ingroup-shared attributes. All selves are fundamental components of the self-concept, with each being important and meaningful to human experience and with each being associated with health benefits. Are the selves,
Sedikides, Constantine   +2 more
openaire   +4 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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