Results 61 to 70 of about 3,965,014 (302)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Characterization and potential usage of selected eggshell species

open access: yesScientific Reports
Today’s awareness of environmental pollution and the idea of creating a reuse area for waste is one of the trend topics. The base opinion, regarding the reuse of any material is that all resources are inherently limited in the world.
Taner Kalaycı   +3 more
doaj   +1 more source

Development of a Smart Wireless Multisensor Platform for an Optogenetic Brain Implant

open access: yesSensors
Implantable cell replacement therapies promise to completely restore the function of neural structures, possibly changing how we currently perceive the onset of neurodegenerative diseases.
André B. Cunha   +15 more
doaj   +1 more source

Limitations of Sem Characterization of Semiconductors

open access: yesMicroscopy and Microanalysis, 1997
Abstract The field of semiconductor materials and devices represents a unique challenge to microscopy and microanalysis because the standard of excellence is constantly changing. Driven by the imperative of Moore's law (illustrated in figure 1) - which predicts that the density of devices in a chip doubles every three years - the spatial
openaire   +1 more source

Physico-chemical characterization of sterilized Fe2O3 nanoparticles by XPS / HAXPES / SEM

open access: yes, 2023
Here a dataset of XPS, HAXPES and SEM measurements for the physico-chemical characterization of sterilized Fe2O3 nanoparticles is presented. The measurements are part of the H2020 project “NanoSolveIT”
Knigge, Xenia, Radnik, Jörg
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Reliability of deep learning models for scanning electron microscopy analysis

open access: yesMachine Learning: Science and Technology
Scanning electron microscopy (SEM) provides high-resolution nanoscale imaging crucial for advanced materials characterization. Recent advancements in deep learning have significantly enhanced SEM analysis by automating the identification of nanoscale ...
Chuen-Wun Pai   +2 more
doaj   +1 more source

Characterizing Crystalline Materials in the SEM

open access: yes, 2017
While amorphous substances such as glass are encountered both in natural and artificial materials, most inorganic materials are found to be crystalline on some scale, ranging from sub-nanometer to centimeter or larger. A crystal consists of a regular arrangement of atoms, the so-called «unit cell,» which is repeated in a two- or three-dimensional ...
Joseph I. Goldstein   +5 more
openaire   +1 more source

Physico-chemical characterization of sterilized Co2.25Fe0.75O4 nanoparticles by XPS / HAXPES / SEM

open access: yes, 2023
Here a dataset of XPS, HAXPES and SEM measurements for the physico-chemical characterization of sterilized Co2.25Fe0.75O4 nanoparticles is presented. The measurements are part of the H2020 project “NanoSolveIT”
Knigge, Xenia, Radnik, Jörg
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

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