Results 301 to 310 of about 2,563,053 (365)

Cognitive Changes in Pre‐ataxic Spinocerebellar Ataxias: A Scoping Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Although traditionally recognized for motor impairment, evidence suggests that cognitive deficits may emerge before ataxia onset in autosomal dominant spinocerebellar ataxias (SCA), particularly in nucleotide repeat expansion SCAs (NRE‐SCAs).
Renata Barreto Tenorio   +3 more
wiley   +1 more source

One Side or Two? A Systematic Review of Deep Brain Stimulation Approaches in Movement Disorders

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) is an established treatment for movement disorders such as Parkinson's disease (PD) and essential tremor (ET). However, the decision between unilateral, staged bilateral, or simultaneous bilateral DBS remains controversial, influenced by clinical presentation, patient preferences, and economic factors ...
Artur Vetkas   +15 more
wiley   +1 more source

Semantic Memory in Healthy Apolipoprotein ε4 Carriers: A Systematic Review

open access: yes
Sacripante R   +4 more
europepmc   +1 more source

Prodromal Lewy Body Symptoms and α‐Synuclein Seeding in Idiopathic Olfactory Dysfunction

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Early identification of pathological α‐synuclein deposition (αSynD) may improve understanding of Lewy body disorder (LBD) progression and enable timely disease‐modifying treatments. Objectives We investigated αSynD using a seed amplification assay and assessed prodromal LBD symptoms in individuals with idiopathic olfactory ...
Oskar Hoffmann McWilliam   +15 more
wiley   +1 more source

Low Frequency of Dementia with Lewy Bodies Diagnosis in a Colombian Memory Clinic

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background The global burden of dementia is increasing, particularly in low‐ and middle‐income countries. Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia but remains underreported and frequently misdiagnosed. Its prevalence in Latin America is largely unknown.
Felipe Botero‐Rodríguez   +6 more
wiley   +1 more source

Discrepant Views of Apathy in Patients and Caregivers: the Role of Cognitive Deficits in Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Apathy is a common early symptom of Parkinson's disease (PD), often co‐occurring with cognitive decline and associated with fronto‐striatal and mesocortico‐limbic dysfunctions. Discrepancies between self‐ and caregiver‐reported apathy have been preliminarily associated with cognitive impairments affecting patients’ awareness and ...
Giulia Funghi   +13 more
wiley   +1 more source

Digital Therapeutics for Alzheimer's and Parkinson's Diseases: Current Trends and Future Perspectives

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) and Parkinson's disease (PD), which are characterized by the accumulation of misfolded protein aggregates and cognitive/motor dysfunction, are the most prevalent neurodegenerative diseases (NDDs). Despite strategic investigations aimed at augmenting the pharmaceutical pipeline, available drugs for AD and PD merely slow
Yoo Joo Jeong   +12 more
wiley   +1 more source

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