Results 301 to 310 of about 2,563,053 (365)
Cognitive Changes in Pre‐ataxic Spinocerebellar Ataxias: A Scoping Review
Abstract Background Although traditionally recognized for motor impairment, evidence suggests that cognitive deficits may emerge before ataxia onset in autosomal dominant spinocerebellar ataxias (SCA), particularly in nucleotide repeat expansion SCAs (NRE‐SCAs).
Renata Barreto Tenorio +3 more
wiley +1 more source
One Side or Two? A Systematic Review of Deep Brain Stimulation Approaches in Movement Disorders
Abstract Background Deep brain stimulation (DBS) is an established treatment for movement disorders such as Parkinson's disease (PD) and essential tremor (ET). However, the decision between unilateral, staged bilateral, or simultaneous bilateral DBS remains controversial, influenced by clinical presentation, patient preferences, and economic factors ...
Artur Vetkas +15 more
wiley +1 more source
Semantic Memory in Healthy Apolipoprotein ε4 Carriers: A Systematic Review
Sacripante R +4 more
europepmc +1 more source
Consolidation improves the learning of new meanings for known words but not necessarily their integration into semantic memory. [PDF]
Fang X, Perfetti CA.
europepmc +1 more source
Prodromal Lewy Body Symptoms and α‐Synuclein Seeding in Idiopathic Olfactory Dysfunction
Abstract Background Early identification of pathological α‐synuclein deposition (αSynD) may improve understanding of Lewy body disorder (LBD) progression and enable timely disease‐modifying treatments. Objectives We investigated αSynD using a seed amplification assay and assessed prodromal LBD symptoms in individuals with idiopathic olfactory ...
Oskar Hoffmann McWilliam +15 more
wiley +1 more source
Low Frequency of Dementia with Lewy Bodies Diagnosis in a Colombian Memory Clinic
Abstract Background The global burden of dementia is increasing, particularly in low‐ and middle‐income countries. Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia but remains underreported and frequently misdiagnosed. Its prevalence in Latin America is largely unknown.
Felipe Botero‐Rodríguez +6 more
wiley +1 more source
Abstract Background Apathy is a common early symptom of Parkinson's disease (PD), often co‐occurring with cognitive decline and associated with fronto‐striatal and mesocortico‐limbic dysfunctions. Discrepancies between self‐ and caregiver‐reported apathy have been preliminarily associated with cognitive impairments affecting patients’ awareness and ...
Giulia Funghi +13 more
wiley +1 more source
ABSTRACT Alzheimer's disease (AD) and Parkinson's disease (PD), which are characterized by the accumulation of misfolded protein aggregates and cognitive/motor dysfunction, are the most prevalent neurodegenerative diseases (NDDs). Despite strategic investigations aimed at augmenting the pharmaceutical pipeline, available drugs for AD and PD merely slow
Yoo Joo Jeong +12 more
wiley +1 more source

