Results 91 to 100 of about 1,189,261 (324)

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

open access: yesAdvanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu   +5 more
wiley   +1 more source

Taboo semantics [PDF]

open access: yes2014 5th IEEE Conference on Cognitive Infocommunications (CogInfoCom), 2014
PUBLISHED IEEE Catalog Number: CFP1426R-USB ISBN 978-1-4799-7279-1 ...
openaire   +2 more sources

Enriching videos with light semantics [PDF]

open access: yes, 2010
This paper describes an ongoing prototypical framework to annotate and retrieve web videos with light semantics. The proposed framework reuses many existing vocabularies along with a video model. The knowledge is captured from three different information
Breslin, John G., Choudhury, Smitashree
core  

Multilingual Models for Compositional Distributed Semantics

open access: yes, 2014
We present a novel technique for learning semantic representations, which extends the distributional hypothesis to multilingual data and joint-space embeddings.
Blunsom, Phil, Hermann, Karl Moritz
core   +1 more source

Leveraging 3D Molecular Spatial Visual Information and Multi‐Perspective Representations for Drug Discovery

open access: yesAdvanced Science, EarlyView.
A deep learning framework called MolVisGNN is proposed to fuse 3D molecular visual information of drugs with multi‐source features, which proves the importance of 3D molecular visual information of drugs and the advancedness of this model in the field of drug discovery, and provides a reference for how to more comprehensively express small molecule ...
Zimai Zhang   +9 more
wiley   +1 more source

Deep learning for predicting the occurrence of tipping points

open access: yesRoyal Society Open Science
Tipping points occur in many real-world systems, at which the system shifts suddenly from one state to another. The ability to predict the occurrence of tipping points from time series data remains an outstanding challenge and a major interest in a broad
Chengzuo Zhuge, Jiawei Li, Wei Chen
doaj   +1 more source

Whither semantics?

open access: yesTheoretical Computer Science, 2020
We discuss how mathematical semantics has evolved, and suggest some new directions for future work. As an example, we discuss some recent work on encapsulating model comparison games as comonads, in the context of finite model theory.
openaire   +2 more sources

The Semantics of Article Acquisition [PDF]

open access: yes, 2019
Accurately using articles has consistently been a difficult task for English language learners as articles are often treated as solely grammatical forms rather than also recognizing as representatives of complex semantic properties.
Renie, Emily G
core   +1 more source

SpaBalance: Balanced Learning for Efficient Spatial Multi‐Omics Decoding

open access: yesAdvanced Science, EarlyView.
SpaBalance is a computational framework that harmonizes multi‐omics learning via gradient equilibrium and dual‐stream feature decomposition, achieving superior clustering accuracy, biological interpretability, and scalable integration of three or more spatial omics modalities.
Yingbo Cui   +8 more
wiley   +1 more source

CELLama: Foundation Model for Single Cell and Spatial Transcriptomics by Cell Embedding Leveraging Language Model Abilities

open access: yesAdvanced Science, EarlyView.
CELLama is created, a framework that harnesses language models to convert cellular data into “sentences” that represent gene expression and metadata, enabling a universal embedding of cells. Unlike most single‐cell foundation models, CELLama supports scalable analysis and offers flexible applications including spatial transcriptomics.
Jeongbin Park   +7 more
wiley   +1 more source

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