MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge +13 more
wiley +1 more source
MARD-Mol: a hybrid autoregressive-diffusion paradigm for coarse-grained molecular modeling. [PDF]
Zhang S, Luo G, Fan W, Lv X, Li M.
europepmc +1 more source
Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution
MCKcat, a deep learning framework combining multi‐scale convolution and cross‐attention, accurately predicts enzyme turnover number (kcat) by fusing sequence and reaction representations. It couples with rational design in a two‐step strategy for Bacillus aryabhattai laccase engineering, achieving a 75% positive rate with synergistically enhanced ...
Fengya Ge +6 more
wiley +1 more source
Adaptive knowledge distillation based structure-text embedding integrating for knowledge graph completion. [PDF]
Li Q +6 more
europepmc +1 more source
DeepLNM: A Multimodal Model for Predicting Lymph Node Metastasis in Colorectal Cancer
Traditional diagnosis may miss positive LNM cases, and pathologists face a workload; therefore, we develop DeepLNM, a multimodal model that predicts lymph node metastasis in colorectal cancer from H&E WSIs, CT images, and text. DeepLNM is robust across internal, external, and prospective cohorts and, in a user study, improves diagnostic accuracy while ...
Zhengyu Zhang +24 more
wiley +1 more source
PCGM-Net: Policy-Conditioned Local Generative Masking for Privacy-Preserving Wi-Fi CSI Sensing. [PDF]
Zhang W +6 more
europepmc +1 more source
A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu +15 more
wiley +1 more source
A reproducible workflow for diagnosing YOLO26-to-NCNN deployment inconsistencies on resource-constrained Android devices. [PDF]
Ma J, Xu L, Li X, Liang Y.
europepmc +1 more source
Anode‐Free Sodium Metal Batteries: From Materials Design to System‐Level Integration
Anode‐free sodium metal batteries hold no sodium reserve, so every inefficiency becomes permanent loss. Resolving the inventory into reversible, dead, and chemically bound fractions exposes what Coulombic efficiency hides. Practical 500‐cycle operation requires above 99.95%, a threshold few systems meet under lean electrolyte and high areal capacity ...
Hamid Hussain +10 more
wiley +1 more source
HD-AIP: a heterogeneous dual-stream alignment-free framework for anti-inflammatory peptide prediction based on language models and CT-Net. [PDF]
Li J +5 more
europepmc +1 more source

