Results 111 to 120 of about 239,048,002 (311)

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

A SCC Recursive Meta-Algorithm for Computing Preferred Labellings in Abstract Argumentation [PDF]

, 2014
This paper presents a meta-algorithm for the computation of preferred labellings, based on the general recursive schema for argumentation semantics called SCC-Recursiveness.
Vallati, Mauro, Giacomin, Massimiliano, Zanella, Marina, Cerutti, Federico   +3 more
core  

Intelligent Distributed Computing VI : Proceedings of the 6th International Symposium on Intelligent Distributed Computing

, 2012
This book represents the combined peer-reviewed proceedings of the Sixth International Symposium on Intelligent Distributed Computing -- IDC~2012, of the International Workshop on Agents for Cloud -- A4C~2012 and of the Fourth International Workshop on ...
Badica, Costin, Fortino, Giancarlo, Unland, Rainer, Malgeri, Michele, Rosaci D, SANTORO, CORRADO, MESSINA, FABRIZIO, PAPPALARDO, Giuseppe, Sarnè G.   +8 more
core   +1 more source

DeepLNM: A Multimodal Model for Predicting Lymph Node Metastasis in Colorectal Cancer

Advanced Science, EarlyView.
Traditional diagnosis may miss positive LNM cases, and pathologists face a workload; therefore, we develop DeepLNM, a multimodal model that predicts lymph node metastasis in colorectal cancer from H&E WSIs, CT images, and text. DeepLNM is robust across internal, external, and prospective cohorts and, in a user study, improves diagnostic accuracy while ...
Zhengyu Zhang, Chengyu Lu, Zhen Wang, Zhijian Cen, Yangshu Zhou, Danyi Li, Qi Xie, Bingbing Li, Shujing Guo, Zhijun Gan, Er‐ran Zhu, Jinbang Li, Aihetaimu Aimaier, Rui Mao, Weihao Qiu, Chenglong Zhao, Ying Tan, Xiaolin Liu, Huiting Ma, Tiansu Geng, Peiyue Wu, Huijun Du, Yu Wang, Yueping Liu, Li Liang   +24 more
wiley   +1 more source

Disentangling Heterogeneous Molecular Networks for Multi‐Omics‐Driven Cancer Driver Discovery

Advanced Science, EarlyView.
DRIVE integrates PPI topology and pan‐cancer multi‐omics profiles through dual‐view graph disentanglement, contrastive representation learning, and joint optimization. Across six PPI networks, DRIVE outperforms ten baselines and remains robust to structural and annotation perturbations.
Xinjing Gong, Ji Li, Mu Su, Peishen Yu, Te Ma, Ruiyang Zhai, Chenye Zhang, Mengyan Zhang, Yan Zhang   +8 more
wiley   +1 more source

The Sigma-Semantics: A Comprehensive Semantics for Functional Programs [PDF]

, 1996
A comprehensive semantics for functional programs is presented, which generalizes the well-known call-by-value and call-by-name semantics. By permitting a separate choice between call-by value and call-by-name for every argument position of every ...
Chitil, O., Olaf Chitil, Chitil, Olaf
core   +1 more source

Editorial: Conceptualizing and Using Theory in Computing Education Research

, 2022
There has been considerable recent interest in a number of questions related to theory within computing education research. In this editorial, we summarize some of this recent interest, discuss the process in which this special issue came to be, and how ...
Malmi, Lauri, Tenenberg, Josh, Lauri Malmi, Josh Tenenberg   +3 more
core   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

qcGEM: A Graph‐Based Molecular Representation With Quantum Chemistry Awareness

Advanced Science, EarlyView.
In this work, we introduce qcGEM, a quantum‐chemistry‐aware graph‐based embedding of molecules that incorporates physical priors into molecular representation learning. Through a specially designed model architecture to adequately process quantum chemistry information as well as three‐dimensional molecular geometry, qcGEM provides a compact, physics ...
Haoyu Wang, Ziyan Zhang, Swee Hong Ng, Haipeng Gong   +3 more
wiley   +1 more source

Inventory theory applied to cost optimization in cloud computing [PDF]

, 2016
Cloud computing providers offer two different pricing schemes when renting virtual machines: reserved instances and ondemand instances. On-demand instances are paid only when utilized and they are useful to satisfy a fluctuating demand.
Jukka K. Nurminen, Nodari, Andrea, Nurminen, Jukka K., Frühwirth, Christian, Andrea Nodari, Christian Frühwirth   +5 more
core   +1 more source