Results 41 to 50 of about 125,940 (271)
Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis
Advanced Science, EarlyView.Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...Francesca Alves, Darius Lane, Adam Wahida, Md. Jakaria, Pawel Kalinowski, Adam Southon, Abdel Ali Belaidi, Teresa Samperi‐Esteve, Triet Phu Minh Nguyen, Peng Lei, Marcus Krueger, Stefan Mueller, Marcus Conrad, Puja Agarwal, Sue E Leurgans, Julie Schneider, Ashley I. Bush, Scott Ayton +17 morewiley +1 more sourceAn Algebraic Framework for Compositional Program Analysis [PDF]
, 2013 The purpose of a program analysis is to compute an abstract meaning for a
program which approximates its dynamic behaviour. A compositional program
analysis accomplishes this task with a divide-and-conquer strategy: the meaning
of a program is computed ...Farzan, Azadeh, Kincaid, Zacharycore SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks
Advanced Science, EarlyView.SCRIPT is a novel method inferring single‐cell cis‐regulatory relationships (CRRs) from transcriptomic and chromatin accessibility data. SCRIPT incorporates two key innovations: graph causal attention networks supported by empirical CRR evidence, and representation learning enhanced through pretraining on atlas‐scale single‐cell data.Yu Zhang, Baole Wen, Yifeng Jiao, Yuchen Liu, Xin Guo, Yushuai Wu, Jiyang Li, Limei Han, Yinghui Xu, Xin Gao, Yuan Qi, Yuan Cheng, Ying He, Weidong Tian +13 morewiley +1 more sourceTruth theories, competence, and semantic computation
, 2012 The paper discusses the question whether T-theories explain how it is possible to understand new sentences, or learn an infinite language, as Davidson claimed. I argue against some commentators that for explanatory power we need not require that T-theories are implicitly known or mirror cognitive structures.openaire +3 more sourcesDynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes
Advanced Science, EarlyView.Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...Zhenhong He, Yifan Du, Ziqi Fu, Youcun Zheng, Nils Muhlert, Barbara Sahakian, Rebecca Elliott +6 morewiley +1 more sourceEuclid: Early Release Observations -- Dwarf galaxies in the Perseus galaxy cluster [PDF]
Astronomy & AstrophysicsWe make use of the unprecedented depth, spatial resolution, and field of view of the Early Release Observations (EROs) of the Perseus galaxy cluster to detect and characterise the dwarf galaxy population in this massive system.F. Marleau, J. Cuillandre, M. Cantiello, D. Carollo, P. Duc, R. Habas, L. Hunt, P. Jablonka, M. Mirabile, M. Mondelin, M. Poulain, T. Saifollahi, R. S'anchez-Janssen, E. Sola, M. Urbano, R. Zoller, M. Bolzonella, A. Lanccon, R. Laureijs, O. Marchal, M. Schirmer, C. Stone, A. Boselli, A. Ferr'e-Mateu, N. A. Hatch, M. Kluge, M. Montes, J. Sorce, C. Tortora, A. Venhola, J. Golden-Marx, N. Aghanim, A. Amara, S. Andreon, N. Auricchio, M. Baldi, A. Balestra, S. Bardelli, P. Battaglia, R. Bender, C. Bodendorf, E. Branchini, M. Brescia, J. Brinchmann, S. Camera, G. Candini, V. Capobianco, C. Carbone, J. Carretero, S. Casas, M. Castellano, S. Cavuoti, A. Cimatti, G. Congedo, C. Conselice, L. Conversi, Y. Copin, F. Courbin, H. Courtois, M. Cropper, A. D. Silva, H. Degaudenzi, A. D. Giorgio, J. Dinis, M. Douspis, C. Duncan, X. Dupac, S. Dusini, A. Ealet, M. Farina, S. Farrens, S. Ferriol, P. Fosalba, S. Fotopoulou, M. Frailis, E. Franceschi, M. Fumana, S. Galeotta, B. Garilli, W. Gillard, B. Gillis, C. Giocoli, P. G'omez-Alvarez, A. Grazian, F. Grupp, L. Guzzo, M. Hailey, S. Haugan, J. Hoar, H. Hoekstra, W. Holmes, I. Hook, F. Hormuth, A. Hornstrup, D. Hu, P. Hudelot, K. Jahnke, M. Jhabvala, E. Keihanen, S. Kermiche, A. Kiessling, T. Kitching, R. Kohley, B. Kubik, K. Kuijken, M. Kummel, M. Kunz, H. Kurki-Suonio, O. Lahav, D. L. Mignant, S. Ligori, P. Lilje, V. Lindholm, I. Lloro, D. Maino, E. Maiorano, O. Mansutti, O. Marggraf, K. Markovič, N. Martinet, F. Marulli, R. Massey, S. Maurogordato, H. McCracken, E. Medinaceli, S. Mei, Y. Mellier, M. Meneghetti, E. Merlin, G. Meylan, Michele Moresco, L. Moscardini, E. Munari, R. Nakajima, R. Nichol, S. Niemi, C. Padilla, S. Paltani, F. Pasian, K. Pedersen, W. Percival, V. Pettorino, S. Pires, G. Polenta, M. Poncet, L. Popa, L. Pozzetti, F. Raison, R. Rebolo, A. Refregier, A. Renzi, J. Rhodes, G. Riccio, H. Rix, E. Romelli, M. Roncarelli, E. Rossetti, R. Saglia, D. Sapone, R. Scaramella, P. Schneider, A. Secroun, G. Seidel, M. Seiffert, S. Serrano, C. Sirignano, G. Sirri, L. Stanco, P. Tallada-Cresp'i, A. Taylor, H. Teplitz, I. Tereno, R. Toledo-Moreo, A. Tsyganov, I. Tutusaus, E. Valentijn, L. Valenziano, T. Vassallo, G. V. Kleijn, A. Veropalumbo, Y. Wang, J. Weller, O. Williams, G. Zamorani, E. Zucca, C. Baccigalupi, A. Biviano, C. Burigana, G. Lucia, K. George, V. Scottez, M. Viel, P. Simon, A. Mora, J. Mart'in-Fleitas, D. S. U. Innsbruck, Institut fur Teilchenphysik, Technikerstr. 258, 6020 Innsbruck, Austria, Universit'e Paris-Saclay, Universit'e de Paris Cit'e, Cea, Cnrs, Aim, 91191, Gif-sur-Yvette, France, I. A. d'Abruzzo, Via M. Maggini, 64100, Teramo, Italy, Inaf Trieste, 11 ViaG.B.Tiepolo, 34127 Trieste, U. Strasbourg, O. Strasbourg, Umr 7550, 67000 Strasbourg, Inaf - Arcetri, 5. LargoE.Fermi, 50125, Firenze, I. O. Physics, L. O. Astrophysics, E. P. F. Lausanne, Observatoire de Sauverny, 1290 Versoix, Switzerland, Gran Sasso Science Institute, 7. VialeF.Crispi, L’Aquila, 67100, S. Physics, A. Unit, U. Oulu, 1. PenttiKaiterankatu, F. Oulu, Finland, O. Strasbourg, U. Cnrs, Strasbourg, K. Institute, U. Groningen, PO Box 800, 9700 AV Groningen, The Netherlands., UK Astronomy Technology Centre, R. Observatory, B. Hill, Edinburgh EH9 3HJ, Uk, I. O. Astronomy, U. Cambridge, Madingley Road, Cambridge CB3 0HA, Universitatssternwarte Munchen, F. Physik, Ludwig-Maximilians-Universitat Munchen, 1. Scheinerstrasse, 8. Munchen, Germany, M. F. P. Physics, 1. Giessenbachstr., 85748 Garching, I. Bologna, V. G. 933, 40129 Bologna, European Space AgencyESTEC, 1. Keplerlaan, 2. Noordwijk, M. Astronomie, 17 Konigstuhl, 69117 Heidelberg, Department of Astronomy Physics, U. Montr'eal, 2900 Edouard Montpetit Blvd, Montr'eal, Qu'ebec H3T 1J4, Canada, A. Universit'e, Cnes, Lam, Marseille, I. D. Cagliari, 5. viadellaScienza, 09047 Selargius, D. Astrof'isica, U. L. Laguna, 38206, La Laguna, Tenerife, Spain., Instituto de Astrof'isica de Canarias, C. V. L. sn, 38204, San Crist'obal de La Laguna, S. O. Physics, Astronomy, U. Nottingham, U. Park, Nottingham NG7 2RD, U. Lille, Centrale Lille, U. 9. CRIStAL, 59000 Lille, I. D. Spatiale, 91405, Orsay, L. F. Astrophysik, 16 AnderSternwarte, 14476 Potsdam, I. -. Capodimonte, 16 viaMoiariello, 80131 Napoli, S. O. Mathematics, Physics, University of Surrey, Guildford, Surrey, GU2 7XH, I. Brera, 28 ViaBrera, 20133 Milano, D. Astronomia, U. Bologna, V. G. 932, I. Bologna, 62 vialeBertiPichat, 40129 Bologna, I. Padova, 5. Viadell'Osservatorio, 35131 Padova, D. Fisica, U. Genova, 33 viaDodecaneso, 16146, Genova, I. Genova, Department of PhysicsE. Pancini, U. Federico, 6. ViaCinthia, 80126, Napoli, I. Naples, I. D. A. E. C. D. Espacco, U. Porto, Caup, Rua das Estrelas, P. Porto, Portugal, F. Porto, Rua do Campo Alegre, 4169-007 Porto, U. Torino, 1. ViaP.Giuria, 10125 Torino, I. Torino, I. Torino, 20 viaOsservatorio, 1. P. Torinese, Mullard Space Science Laboratory, U. London, H. Mary, Dorking, Surrey RH5 6NT, Inaf-Iasf Milano, 12 ViaAlfonsoCorti, 20133 Milano, Centro de Investigaciones Energ'eticas, Medioambientales y Tecnol'ogicas, 40 AvenidaComplutense, 28014 Madrid, Port d'Informaci'o Cient'ifica, Campus Uab, C. Sn, 08193 Bellaterra, I. F. Physics, Cosmology, Rwth Aachen University, 52056 Aachen, I. Roma, 33 viaFrascati, 00078 Monte Porzio Catone, D. Bologna, Institute for Astronomy, U. Edinburgh, J. B. C. F. Astrophysics, U. Manchester, Oxford Road, M13 9PL, European Space AgencyESRIN, 1. LargoGalileoGalilei, 00044 Frascati, Roma, Esacesa, Camino Bajo de Castillo, sn., Urb. Villafranca del Castillo, 28692 Villanueva de la Canada, Madrid, 1. Universit'eClaudeBernardLyon, CNRSIN2p3, I. Lyon, Umr 5822, Villeurbanne, F-69100, 1. UCBLyon, Iuf, 4. R. E. Fermi, 69622 Villeurbanne, D. D. F'isica, F. Ciencias, Universidade de Lisboa, C8 Edif'icio, C. Grande, P. Lisboa, 1049-001 Lisboa, D. O. Astronomy, U. Geneva, 16 ch.d'Ecogia, I. D. A. E. P. Spaziali, V. Cavaliere, 100, 00133 Roma, INFN-Padova, 8. viaMarzolo, 35131 Padova, I. D. E. D. Catalunya, Edifici Rdit, C. Upc, 08860 Castelldefels, Barcelona, Institut de Ci'encies de l'Espai, Carrer de Can Magrans, sn Cerdanyola del Vall'es, 08193 Barcelona, H. P. Laboratory, U. Bristol, Tyndall Avenue, Bristol, BS8 1TL, Cppm, Istituto Nazionale Fisica Nucleare, Sezione Infn di Bologna, 46 ViaIrnerio, 40129 Bologna, Fractal S.L.N.E., 2. calleTulip'an, 1A Portal13, 28231, L. Madrid, Dipartimento di FisicaAldo Pontremoli, U. Milano, 16 viaCeloria, Institute of Theoretical Astrophysics, U. Oslo, P. O. B. 1. Blindern, 0315 Oslo, Norway, L. Observatory, Leiden University, 55 Einsteinweg, 2333 CC Leiden, Jet propulsion Laboratory, C. I. O. Technology., 4800 Oak Grove Drive, Pasadena, Ca, 91109, Usa, L. University, Lancaster, LA1 4YB, Felix Hormuth Engineering, 17 Goethestr., 69181 Leimen, T. Denmark, Elektrovej 327, 2800 Kgs. Lyngby, Denmark, Cosmic Dawn Center, I. Paris, Umr 7095, Sorbonne Universit'e, 98 bis boulevard Arago, 7. Paris, Nasa Goddard Space Flight Center, Greenbelt, MD 20771, H. I. O. Physics, 2. GustafHallstrominkatu, 0. Helsinki, U. Geneve, D'epartement de Physique Th'eorique, Centre for Theoretical Physics, 24 quai Ernest-Ansermet, 4. CH-1211Geneve, 64 P.O.Box +499 moresemanticscholar +1 more source
