Results 41 to 50 of about 4,358 (218)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Epidemic Dynamics via Wavelet Theory and Machine Learning with Applications to Covid-19

Biology, 2020
We introduce the concept of epidemic-fitted wavelets which comprise, in particular, as special cases the number I(t) of infectious individuals at time t in classical SIR models and their derivatives.
Tô Tat Dat, Protin Frédéric, Nguyen T. T. Hang, Martel Jules, Nguyen Duc Thang, Charles Piffault, Rodríguez Willy, Figueroa Susely, Hông Vân Lê, Wilderich Tuschmann, Nguyen Tien Zung   +10 more
doaj   +1 more source

Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability

Advanced Engineering Materials, EarlyView.
This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner, Geo Jacob, Florian Raddatz, Gerko Wende   +3 more
wiley   +1 more source

GIS Application to Regional Geological Structure Relationship Modelling Considering Semantics

ISPRS International Journal of Geo-Information, 2018
GIS modelling, which is often employed to establish the abstract structural forms of geological phenomena and their structural relationships, is of great importance for the expression and analysis of geological structures to describe and express such ...
Handong He, Di Hu, Guonian Lü
doaj   +1 more source

A Concept of a Digital and Traceable Manufacturing Documentation Based on Formalized Process Description Applied on Composite Aircraft Moveable

Advanced Engineering Materials, EarlyView.
The documentation of component manufacture has become an essential part of today's production processes, especially for the analysis and optimization of production or component design with regard to structural performance, economic efficiency, and sustainability.
Björn Denker, Dominik Delisle, Christian Krombholz, Martin Rädel, Frank Dressel   +4 more
wiley   +1 more source

Evaluating the Role of Entropy Change in Lithium-Ion Battery Electro-Thermal Modelling

Batteries
The accurate estimation of lithium-ion cell internal temperature is crucial for the safe operation of battery packs, especially during high discharge rates, as operating outside the safe temperature range can lead to accelerated degradation or ...
Félix-Antoine LeBel, Pascal Messier, Mathieu Blanchard, João Pedro F. Trovão   +3 more
doaj   +1 more source

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source

A Built Heritage Information System Based on Point Cloud Data: HIS-PC

ISPRS International Journal of Geo-Information, 2020
The digital management of an archaeological site requires to store, organise, access and represent all the information that is collected on the field.
Florent Poux, Roland Billen, Jean-Paul Kasprzyk, Pierre-Henri Lefebvre, Pierre Hallot   +4 more
doaj   +1 more source

Joint Torque Prediction via Hybrid Neuromusculoskeletal Modelling during Gait Using Statistical Ground Reaction Estimates: An Exploratory Study

Sensors, 2021
Joint torques of lower extremity are important clinical indicators of gait capability. This parameter can be quantified via hybrid neuromusculoskeletal modelling that combines electromyography-driven modelling and static optimisation.
Shui Kan Lam, Ivan Vujaklija
doaj   +1 more source