ALDH1A3 promotes the lung metastatic organotropism of pancreatic ductal adenocarcinoma through semaphorin signaling. [PDF]
Shen S +15 more
europepmc +1 more source
Integrative eQTL and Multi-Omics Analysis Reveals the Role of N6-Methyladenosine Modification in Polycystic Ovary Syndrome and Predictive Model Construction. [PDF]
Jin M, Xi S, Ma L.
europepmc +1 more source
Expression analysis and possible functional roles of semaphorin/plexin/CRMP families in mouse pancreatic islets. [PDF]
Kyohara M +13 more
europepmc +1 more source
Human Chorionic Gonadotropin (hCG)-Induced Remodeling of the Granulosa Cell Exosomal Proteome: Implications for Follicular Communication. [PDF]
Mancini F +12 more
europepmc +1 more source
Bimodal Genomic Approach Predicting Semaphorin 7A (SEMA7A) as Prognostic Biomarker in Adrenocortical Carcinoma. [PDF]
Dhall A +13 more
europepmc +1 more source
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Semaphorin class 3C, vascular permeability, and the swollen injured kidney
Kidney International, 2022Class 3 semaphorins (SEMA3) are secreted glycoproteins with established roles in the developing brain, heart, and kidney. In this issue of Kidney International, Cai et al. show that in acutely injured kidneys, semaphorin isoform SEMA3C is expressed de novo in glomeruli and the nephron, secreted into the circulation, and excreted into the urine ...
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Semaphorins 3A, 3C, and 3F in mesencephalic dopaminergic axon pathfinding
Journal of Comparative Neurology, 2007AbstractBy analyzing the mechanisms that govern dopaminergic axon pathfinding from the midbrain to the striatum in embryonic rat brains, we identified neuroepithelial regions that exert chemotropic effects on mesencephalic dopaminergic axons. Explants from the pretectum and the striatum showed an attractive effect, whereas those from the midhindbrain ...
Hebert L, Hernández-Montiel +3 more
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Semaphorin 3C regulates endothelial cell function by increasing integrin activity
The FASEB Journal, 2006Class 3 semaphorins (sema 3) are secreted guidance proteins. Sema 3A expressed by endothelial cells controls vascular morphogenesis through integrin inhibition. Sema 3C is required for normal cardiovascular patterning. Here we examined the potential role of sema 3C as regulator of endothelial cell function in ...
Nazifa Banu +9 more
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Reduced Sympathetic Innervation in Endometriosis is Associated to Semaphorin 3C and 3F Expression
Molecular Neurobiology, 2016Endometriosis is a chronic inflammatory disease and one of the most common causes of pelvic pain. The mechanisms underlying pain emergence or chronic inflammation during endometriosis remain unknown. Several chronic inflammatory diseases including endometriosis show reduced amounts of noradrenergic nerve fibers.
Scheerer, C +3 more
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Renal Semaphorin 3C mediates cardiac adaptive response
European Heart JournalAbstract Cardiorenal syndrome, characterized by reciprocal heart-kidney interactions that progressively promote dysfunction in both organs, is associated with a high mortality rate. However, the mechanisms linking the two organs are insufficiently understood.
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