Results 61 to 70 of about 110,214 (295)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Identification of Armeniacae Semen and Persicae Semen

The Korea Journal of Herbology, 2014
ABSTRACT Objectives : To present a differential standard of Armeniacae Semen and Per sicae Semen that are easily confused.Methods : It was planed a differential standard form through outer appea rance of the original plant, outer appearance in the form of each medicines and the appearance of the interior form through a microscope for each samples ...
Young-Sung Ju, Young Sik Kim, Goya Choi, Guemsan Lee, Seung Ho Lee, Jung-Hoon Kim   +5 more
openaire   +3 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

PERANCANGAN DAN IMPLEMENTASI SISTEM E-COMMERCE PADA UMKM BATIK DI KABUPATEN JOMBANG

Dinamisia, 2019
The rapid development of information technology (IT) is directly proportional to the increase of the middle-class economy segment. As one of the original products of the Indonesian people, batik and all its variety is not spared from the impact of IT ...
Renny Sari Sisfor, Oki Anita Candra Dewi, Rizky Noviasri   +2 more
doaj   +1 more source

Review Industri Semen

, 2019
Industri semen nasional adalah industri strategis yang sangat dibutuhkan dalam setiap negara. Tujuan dari pembuatan jurnal ini adalah untuk mengetahui sejarah semen, proses produksi semen dan industri semen. Metode penelitian yang digunakan adalah metode studi kepustakaan. Kesimpulan dari jurnal ini sebagai berikut perusahaan semen pertama di Indonesia
Febri Andini, Laila Suryani, Hildayati Amri   +2 more
openaire   +4 more sources

The tumor–microbe connection

Molecular Oncology, EarlyView.
Tumor‐associated bacteria (TAB) dynamically influence cancer biology by modulating tumor progression, metastatic spread, and therapeutic efficacy. Their presence redefines the tumor microenvironment (TME) as a microbial–host interface, yet mechanistic insights remain limited. Understanding TAB colonization routes, functional impacts, and crosstalk with
Gerlanda Vella, Maria Rescigno
wiley   +1 more source

Peran Gaya Kepemimpinan dan Kompensasi dalam Mempengaruhi Kinerja yang Dimediasi oleh Kepuasan Kerja

Jurnal Ekonomi Modernisasi, 2017
The purpose of research to determine the influence of leadership style and compensation on employee performance through job satisfaction as intervening variable with quantitative approach conducted at the head office of PT Varia Usaha, Gresik. Methods of
Mirza Dwinanda Ilmawan, Dwi Setia Wulandar, Fatmala Fitriani   +2 more
doaj  

Factors That Determined University Selection (Case Study on High School/Vocational High School Students in Sidoarjo)

IJEBD (International Journal of Entrepreneurship and Business Development), 2018
Competition between universities in attracting prospective students is now getting tighter, the competition that occurs today is not only applicable among private universities, but it seems that state universities also enliven the arena of prospective ...
Hadi Cahyono, Atikah Aghdhi Pratiwi
doaj   +1 more source