Results 41 to 50 of about 8,356 (256)

Boar semen proteomics and sperm preservation

Theriogenology, 2019
Recently numerous proteomic approaches have been undertaken to identify sperm and seminal plasma (SP) proteins that can be used as potential biomarkers for sperm function, including fertilization ability. This review aims firstly to briefly introduce the proteomic technologies and workflows that can be successfully applied for sperm and SP proteomic ...
Parrilla, I., Perez-Patino, C., Li, J., Barranco, I., Padilla, L., Rodriguez-Martinez, Heriberto, Martinez, E. A., Roca, J.   +7 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

PENGARUH PENGGANTIAN BOVINE SERUM ALBUMIN (BSA) DENGAN PUTIH TELUR DALAM PENGENCER DASAR Cep-2 TERHADAP KUALITAS SEMEN KAMBING BOER PADA SIMPAN DINGIN

Jurnal Ternak Tropika, 2017
The purpose of this research wasinvestigated the substitution effect of Bovine Serum Albumin (BSA) with albumen on CEP-2 diluent to semen quality of Boer goat that was stored at 3-50C.
Ayu Sulvi Istanty, M Ade Salim, Nurul Isnaini, Trinil Susilawati   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Review of Sustainable Cryopreservation and Above-Freezing Storage Solutions of European Honey Bee Apis mellifera Drone Semen

Environmental and Climate Technologies, 2023
The European honey bee Apis mellifera is the main pollinator for most crops used for human consumption. However, a number of diseases, parasites, pesticides and other factors that generally result in the widely described colony collapse disorder weakens ...
Smilga-Spalvina Agnese, Spalvins Kriss, Veidenbergs Ivars   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Effect of chitosan on buck semen quality and semen plasma metabolites during low-temperature storage

Frontiers in Veterinary Science
BackgroundOptimizing buck semen preservation techniques can significantly advance the goat industry. This study aimed to investigate the effects of chitosan on sperm quality and seminal plasma metabolite profiles in bucks during low-temperature storage ...
Meijun Song, Meijun Song, Bingke Jia, Bingke Jia, Dinghui Dai, Dinghui Dai, Xiaoli Xu, Xiaoli Xu, Jiaxue Cao, Jiaxue Cao, Jiazhong Guo, Jiazhong Guo, Linjie Wang, Linjie Wang, Tao Zhong, Tao Zhong, Siyuan Zhan, Siyuan Zhan, Li Li, Li Li, Hongping Zhang, Hongping Zhang   +21 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source