Results 51 to 60 of about 39,957 (261)

Spatiotemporal trends in human semen quality

open access: yesNature Reviews Urology, 2022
Over the past four decades, studies of various designs have reported spatial and temporal trends in human semen quality. Several standardized-methodology studies in homogeneous populations that compare specific cities within a country or a continent provide clear evidence of geographical differences in sperm production, even over short distances within
Auger, Jacques   +3 more
openaire   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Negative association of atmospheric pollutants with semen quality: A cross-sectional study in Taiyuan, China

open access: yesEcotoxicology and Environmental Safety
Background: In recent decades, the quality of male semen has decreased worldwide. Air pollution has been linked to lower semen quality in several studies.
Ke Cai   +8 more
doaj   +1 more source

EXPRESSION OF GLYCOPROTEIN gD AND EVALUATION OF IMMUNE RESPONSE OF BOVINE HERPES VIRUS TYPE-1 IN BUFFALO [PDF]

open access: yesExploratory Animal and Medical Research, 2012
Bovine Herpes Virus type-1 (BoHV-1) causes a multitude of clinical symptoms in cattle, buffaloes and small ruminants. No effective live attenuated or killed vaccine is currently available and extensive research work in progress towards the development of
Sumit Chowdhury   +2 more
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Correlation Analysis of Sperm Cryopreservation Quality with Serum Testosterone and Sperm gDNA Methylation Levels in Xiaoshan Chickens

open access: yesAnimals
Chicken semen cryopreservation is crucial for utilizing high-quality cockerel genetics, but semen is highly sensitive to cryoinjury, leading to poor preservation outcomes. This study aimed to establish a theoretical foundation for selecting cockerels for
Xue Du   +7 more
doaj   +1 more source

Associations between semen phytoestrogens concentrations and semen quality in Chinese men

open access: yesEnvironment International, 2019
Background: Phytoestrogens (PEs) are naturally estrogen-like chemicals, and increasing evidences have indicated their endocrine disruption effects on male reproductivity, but the conclusions from previous epidemiological studies were controversial ...
Guanxiang Yuan   +8 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

The Quality of Frozen Semen Sexing with Percoll Medium and Bovine Serum Albumin (BSA) in Dorper Sheep and Saanen Goat [PDF]

open access: yesE3S Web of Conferences
The study aimed to determine the quality of frozen semen sexing with percoll medium and Bovine Serum Albumin (BSA) in Dorper sheep and Saanen goats. The research was designed based on the experimental method, as the main plot is livestock (M) consisting ...
Sumaryadi Mas Y.   +5 more
doaj   +1 more source

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