Results 31 to 40 of about 1,898 (263)

Abadie Type Constraint Qualifications and Optimality Conditions for Nonsmooth Multi-Objective Semi-Infinite Problems [PDF]

Control and Optimization in Applied Mathematics
This paper introduces several Abadie-type constraint qualifications and derives necessary optimality conditions in the Karush-Kuhn-Tucker for both weakly efficient solutions and efficient solutions of a nonsmooth multi-objective semi-infinite programming
Ahmad Rezaee
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Robust Semi-Infinite Interval Equilibrium Problem Involving Data Uncertainty: Optimality Conditions and Duality

Axioms
In this paper, we model uncertainty in both the objective function and the constraints for the robust semi-infinite interval equilibrium problem involving data uncertainty.
Gabriel Ruiz-Garzón, Rafaela Osuna-Gómez, Antonio Rufián-Lizana, Antonio Beato-Moreno   +3 more
doaj   +1 more source

Dual Set-Membership State Estimation for Power Distribution Networks Under Event-Triggered Mechanism

Frontiers in Energy Research, 2022
This article is concerned with the set-membership state estimation problem for power distribution networks (PDNs) over a resource-constrained communication network under the influence of unknown but bounded (UBB) noises.
Xingzhen Bai, Guhui Li, Mingyu Ding, Xingquan Ji, Jing Li, Xinlei Zheng   +5 more
doaj   +1 more source

Copositive Programming via Semi-Infinite Optimization

Journal of Optimization Theory and Applications, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Faizan Ahmed, Mirjam Dür, Georg Still
openaire   +2 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Second-order optimality conditions for interval-valued functions

Journal of Inequalities and Applications, 2023
This work is included in the search of optimality conditions for solutions to the scalar interval optimization problem, both constrained and unconstrained, by means of second-order optimality conditions.
Gabriel Ruiz-Garzón, Rafaela Osuna-Gómez, Antonio Rufián-Lizana, Antonio Beato-Moreno   +3 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source