Results 31 to 40 of about 2,967,183 (293)

Numerical experiments in semi-infinite programming [PDF]

open access: yes, 1993
A quasi-Newton algorithm for semi-infinite programming using an L∞ exact penalty function is described, and numerical results are presented. Comparisons with three Newton algorithms and one other quasi-Newton algorithm show that the algorithm is very
Coope, I. D., Price, Christopher John
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

On Nonsmooth Semi-Infinite Minimax Programming Problem with (Φ,ρ)-Invexity

open access: yesAbstract and Applied Analysis, 2014
We are interested in a nonsmooth minimax programming Problem (SIP). Firstly, we establish the necessary optimality conditions theorems for Problem (SIP) when using the well-known Caratheodory's theorem.
X. L. Liu   +3 more
doaj   +1 more source

A reduction method for semi-infinite programming by means of a global stochastic approach [PDF]

open access: yes, 2009
We describe a reduction algorithm for solving semi-infinite programming problems. The proposed algorithm uses the simulated annealing method equipped with a function stretching as a multi-local procedure, and a penalty technique for the finite ...
Pereira, Ana I. P. N.   +3 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Abadie Type Constraint Qualifications and Optimality Conditions for Nonsmooth Multi-Objective Semi-Infinite Problems [PDF]

open access: yesControl and Optimization in Applied Mathematics
This paper introduces several Abadie-type constraint qualifications and derives necessary optimality conditions in the Karush-Kuhn-Tucker for both weakly efficient solutions and efficient solutions of a nonsmooth multi-objective semi-infinite programming
Ahmad Rezaee
doaj   +1 more source

A perturbation method for solving linear semi-infinite programming problems [PDF]

open access: yes, 1999
This paper discusses a class of linear semi-infinite programming problems with finite number of variables and infinitely many constraints over a compact metric space. The “adding constraint method” for solving linear semi-infinite programming problems is
Wang, M.-H., Kuo, Y.-E.
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

A solution method for combined semi-infinite and semi-definite programming [PDF]

open access: yes, 2004
In this paper, we develop a discretisation algorithm with an adaptive scheme for solving a class of combined semi-infinite and semi-definite programming problems.
Yang, X. Q., Li, S. J.
core   +3 more sources

Home - About - Disclaimer - Privacy