Results 31 to 40 of about 16,647 (299)
A projected lagrangian algorithm for semi-infinite programming [PDF]
Mathematical Programming, 1985 The authors consider nonlinear semi-infinite optimization problems of type min\(\{\) f(a)\(|\) g(x,a)\(\leq 0\) for all \(x\in X\}\) with a box \(X\subset {\mathbb{R}}^ N\), and \(C^ 2\)-functions f, g. Under appropriate regularity assumptions one may consider the local maxima (w.r.t. variable x) of g(x,a) as functions \(x^ i(a)\) of a, and the problem
Ian D. Coope, G. Alistair Watson
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
On Nonsmooth Semi-Infinite Minimax Programming Problem with (Φ,ρ)-Invexity
Abstract and Applied Analysis, 2014 We are interested in a nonsmooth minimax programming Problem (SIP). Firstly, we establish the necessary optimality conditions theorems for Problem (SIP) when using the well-known Caratheodory's theorem.
X. L. Liu +3 more
doaj +1 more source
Parametric linear semi-infinite programming
, 1996 By using the theory of parametric semi-infinite programming, we show that the solution of a linear semi-infinite programming problem can be obtained by solving a sequence of optimization problems with a single ...
Wu, Soon-Yi, Lin, C.-J., Fang, S.-C.
core +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Abadie Type Constraint Qualifications and Optimality Conditions for Nonsmooth Multi-Objective Semi-Infinite Problems [PDF]
Control and Optimization in Applied MathematicsThis paper introduces several Abadie-type constraint qualifications and derives necessary optimality conditions in the Karush-Kuhn-Tucker for both weakly efficient solutions and efficient solutions of a nonsmooth multi-objective semi-infinite programming
Ahmad Rezaee
doaj +1 more source
Semi-infinite generalized disjunctive and mixed integer convex programs with(out) uncertainty
, 2023 In this paper, we introduce semi-infinite generalized disjunctive programs that are defined by logical propositions along with disjunctions of sets of logical equations and infinite number of algebraic inequalities.
Bansal, Manish
core
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source