Results 61 to 70 of about 18,734 (258)

Proper account of auto-correlations improves decoding performances of state-space (semi) Markov models

open access: yesPeer Community Journal
State-space models are widely used in ecology to infer hidden behaviors. This study develops an extensive numerical simulation-estimation experiment to evaluate the state decoding accuracy of four simple state-space models.
Bez, Nicolas   +8 more
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Building phenotypic character matrices for phylogenetic inference: exploration of 35 years of practice

open access: yesBiological Reviews, EarlyView.
ABSTRACT Recent methodological development in phylogenetic inference has focused predominantly on molecular data. However, renewed interest in other data types, particularly morphological data, has followed from the increased recognition of the power of total evidence and tip‐dating approaches, including fossil data, for inference of time‐scaled trees ...
Melanie J. Hopkins   +9 more
wiley   +1 more source

Joint Tracking of Manoeuvring Targets and Classification of Their Manoeuvrability

open access: yesEURASIP Journal on Advances in Signal Processing, 2004
Semi-Markov models are a generalisation of Markov models that explicitly model the state-dependent sojourn time distribution, the time for which the system remains in a given state.
Maskell Simon
doaj   +1 more source

Research of reliability and efficiency of technological processes of mechanical assembly production on the basis of the common semi-Markov model

open access: yesMATEC Web of Conferences, 2018
In the article a common semi-Markov mathematical model is considered that allows one to investigate the productivity and reliability of various technological processes of mechanical assembly production.
Rapatskiy Yuri   +5 more
doaj   +1 more source

Variance Swap Pricing under Markov-Modulated Jump-Diffusion Model

open access: yesDiscrete Dynamics in Nature and Society, 2021
This paper investigates the pricing of discretely sampled variance swaps under a Markov regime-switching jump-diffusion model. The jump diffusion, as well as other parameters of the underlying stock’s dynamics, is modulated by a Markov chain representing
Shican Liu   +3 more
doaj   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke   +12 more
wiley   +1 more source

Homogeneous Continuous-Time, Finite-State Hidden Semi-Markov Modeling for Enhancing Empirical Classification System Diagnostics of Industrial Components

open access: yesMachines, 2018
This work presents a method to improve the diagnostic performance of empirical classification system (ECS), which is used to estimate the degradation state of components based on measured signals.
Francesco Cannarile   +4 more
doaj   +1 more source

Reweighting Scheme for the Calculation of Grand‐Canonical Expectation Values in Quantum Monte Carlo Simulations With a Fermion Sign Problem

open access: yesContributions to Plasma Physics, EarlyView.
ABSTRACT Ab initio path integral Monte Carlo (PIMC) simulations constitute the gold standard for the estimation of a broad range of equilibrium properties of a host of interacting quantum many‐body systems spanning a broad range of conditions from ultracold atoms to warm dense quantum plasmas.
Paul Hamann   +2 more
wiley   +1 more source

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