Results 151 to 160 of about 10,493 (262)

Steering semi-flexible molecular diffusion model for structure-based drug design with reinforcement learning. [PDF]

Sci Adv
Zhang X, Qu S, Lu F, Wang J, Tian Z, Gu S, Zhang Y, Knoll A, Gao S, Chen G, Jiang C.   +10 more
europepmc   +1 more source

There Is Always a Bigger Fish. Determinants of Power Perceptions in Swiss Biodiversity Policy

Policy Studies Journal, EarlyView.
ABSTRACT The Advocacy Coalition Framework (ACF) views power as crucial in policy processes, but the nature of coalition power, its determinants, and how to empirically measure it remain understudied. In this article, we use a mixed method approach and social network analysis to explore power relationships in the biodiversity policy subsystem in ...
Alix d'Agostino, Jascha Egli, Daniel Kübler   +2 more
wiley   +1 more source

Mathematical Modeling of Amoxicillin Synthesis in Batch and Semi-Batch Reactor: Application of Bayesian Statistics and Genetic Algorithm. [PDF]

Biotechnol Bioeng
Formigosa LF, Dos Santos IC, Alves E Álvares LE, Macêdo EN, Gonçalves LRB, Viegas BM.   +5 more
europepmc   +1 more source

Bayesian Estimation of Transition Rates in Two‐State Nonhomogeneous Markov Jump Processes With Intermittent Observations: An Honest‐Time Data‐Augmentation Approach

Scandinavian Journal of Statistics, EarlyView.
ABSTRACT A possibly time‐dependent transition intensity matrix or generator (Q(t))$$ \left(Q(t)\right) $$ characterizes the law of a Markov jump process (MP). For a time‐homogeneous MP, the transition probability matrix (TPM) can be expressed as a matrix exponential of Q$$ Q $$.
Dario Gasbarra, Sangita Kulathinal, Etienne Sebag   +2 more
wiley   +1 more source

Identification and quantification of irreversibility in stochastic systems.

Phys Chem Chem Phys
Ghosal A, Bisker G.
europepmc   +1 more source

A minimal chemo-mechanical Markov model for rotary catalysis of F₁-ATPase. [PDF]

Nat Commun
Chen Y, Grubmüller H.
europepmc   +1 more source

Bayesian inference of a spatially dependent semi-Markovian model with application to Madagascar Covid'19 data. [PDF]

PLoS One
Raherinirina A, Tsilefa ST, Nirilanto T, Manou-Abi SM.   +3 more
europepmc   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Multiscale mechanistic modelling of heterogeneity in cardiac sub‐cellular calcium handling accounting for variable t‐system density

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of spatial calcium dynamics (left panels) and the state cycle approximation (middle panel) that enables reduced simulation of spatially dependent dynamics without explicit description of space (right panels). The selected example here illustrates a spontaneous calcium wave, showing temporal snapshots of local calcium
Michael A Colman, Yohannes Shiferaw, David Conesa   +2 more
wiley   +1 more source

Algebraic Invariants for Inferring 4-Leaf Semi-Directed Phylogenetic Networks. [PDF]

Syst Biol
Martin S, Holtgrefe N, Moulton V, Leggett RM.   +3 more
europepmc   +1 more source