Results 161 to 170 of about 3,172,165 (245)

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

Towards routine biomechanical data collection in stroke rehabilitation: a usability comparison of IMU and markerless motion capture systems for functional upper-limb assessments. [PDF]

J Neuroeng Rehabil
Unger T, Yao X, Schmitt A, Cebulla L, Easthope Awai C.   +4 more
europepmc   +1 more source

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

Advanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi, Timothy P. Padera, Lance L. Munn   +2 more
wiley   +1 more source

Emotional Dependency and Parasocial Grief Following the Alteration or Loss of Companion Artificial Intelligences: A Systematic Review. [PDF]

Behav Sci (Basel)
Ponce JLA, Vélez WAZ, Zavala GS, Mejillones JMP, Ruiz JCR.   +4 more
europepmc   +1 more source

Nonlinear Ion‐Specific Control of Underwater Adhesion by Bottlebrush Polymer Interfaces

Advanced Science, EarlyView.
The efficiency of underwater adhesion is modulated by ion‐specific effects. Strongly hydrated Na+ remains separated from the mica surface by its hydration shell, preserving access to binding sites, whereas weakly hydrated K+ can partially dehydrate and occupy ditrigonal cavities.
Chang‐Sheng Wang, Hui Guo, Hu Zhang, Duy Anh Pham, Nahid Hassanpour, Wojciech Raj, Qiang Peng, Justine Saber, Tzu‐Hsuan Huang, Florina G. Halmac, Xavier Banquy   +10 more
wiley   +1 more source

Construction and validation of a three-dimensional CT spatial localization algorithm for segond fracture based on tibial bony landmarks: an anatomical reference study for AI-assisted preoperative planning. [PDF]

Front Med (Lausanne)
Guo Z, Yang C, Zheng Y, Zhao Q, Chen N, Ding Y, Chen Q, Pan L, Zhou C.   +8 more
europepmc   +1 more source

Violence exposure among adolescent psychiatric patients in Nepal: Socio-demographic and familial risk factors. [PDF]

PLoS One
Sah R, Brøndbo PH, Handegård BH, Ma J, Hansen KL, Devkota N, Javo AC.   +6 more
europepmc   +1 more source

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

Advanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou, Jianing Jing, Zhuohan Shi, Lei Sun   +3 more
wiley   +1 more source

Bilateral Semi Precision Removable Partial Denture Using Ceka Preci-Sagix Attachment System

Indian Journal of Dental Advancements, 2016
openaire   +1 more source

Precision Ag Workshop

This collection, provided by Clark State Community College, includes resources related to a precision agriculture workshop for high school teachers. Precision agriculture workshops were "designed for high school agriculture/STEM teachers to ...

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