Results 201 to 210 of about 79,466 (260)

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

The use of humanure for cereal production under conventional and regenerative farming models - findings from a three-year grassland-to-arable transition. [PDF]

PLoS One
Allen K, Papargyropoulou E, Wade R, Evans B.   +3 more
europepmc   +1 more source

Senomorphic Small Extracellular Vesicles Delivered by a Tissue‐Adhesive α‐Lipoic‐Acid Hydrogel Enable Immuno‐Rejuvenation for Bone‐Tendon Interface Regeneration

Advanced Science, EarlyView.
This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong, Wei Song, Wencai Liu, Hui Xu, Yuhao Yu, Xinyue Yang, Haiyan Li, Yanlun Zhu, Yaohua He   +8 more
wiley   +1 more source

Circulating Metabolites Treat Human TMJ-OA by Eliminating Senescent Chondrocytes via the C1QBP/C1q/p14ARF Axis. [PDF]

J Extracell Vesicles
Meng B, Li X, Yang B, Qu Y, He Y, Fu C, An Z, Wu A, Hei Y, Zhang R, Cai W, Kong L, Li R, Hao M, Cao Z, Mao X, Pathak JL, Cao Y, Shi S, Zhang Q.   +19 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Engineering a Virus‐Derived X Family DNA Polymerase FvPolX for de novo DNA Synthesis

Advanced Science, EarlyView.
In this study, a Faustovirus‐derived polymerase (FvPolX) is engineered based on structural and sequence analysis of PolX enzymes. The optimal mutants demonstrate substantially enhanced catalytic activity toward dNTPs and 3′‐ONH2‐dNTPs compared to the wild‐type enzyme.
Chengjie Zhang, Lei Du, Shengying Li
wiley   +1 more source

Tendon gel using the film model method promotes ligament healing in rabbits. [PDF]

Arch Orthop Trauma Surg
Yoshimizu R, Nakase J, Yoshioka K, Kuzumaki T, Torigoe K, Demura S.   +5 more
europepmc   +1 more source

Toward Fast‐Charging Polymer‐Electrolyte Based All‐Solid‐State Li–S Batteries: Insights into Limiting Factors and Perspectives

Advanced Science, EarlyView.
The schematic illustrates the important design strategies for polymer solid electrolyte‐based all‐solid‐state lithium‐sulfur batteries (ASSLSBs), including improved ionic conductivity, reduced polysulfide shuttling, stabilized electrode‐electrolyte interfaces, and lithium dendrite mitigation for developing high power and fast charging ASSLSBs ...
S. Jayasubramaniyan, Mingxu Li, Hyeok‐jin Kwon, Sang Yong Nam, Younki Lee, Hyun Woo Kim   +5 more
wiley   +1 more source

Optimized personnel flow with minimal contamination: development and validation of an air-barrier cleanroom for cell products processing. [PDF]

Regen Ther
Mizuno M, Tani H, Nomura K, Sone D, Amano K, Tominaga G, Chiba Y, Sekiya I.   +7 more
europepmc   +1 more source

Heterointerface‑Enabled Electrocatalysis for Efficient Energy Conversion

Advanced Science, EarlyView.
Functionally distinct A/B materials can be integrated at the nanoscale to create customized heterointerfaces with tunable band alignment and charge redistribution, providing fast electron and ion transport channels as well as cooperative dual active sites.
Liuru Fang, Hsiwen Wu, Hengyue Xu, Jie Zhang   +3 more
wiley   +1 more source