Results 41 to 50 of about 1,515,151 (301)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Semi-Rigid Molecular-Clip-Based Molecular Crystal Gearshift

open access: yes, 2018
A new version of molecular clip, with a semi-rigid symmetrical crab-type architecture and flexible cavity size, has been successfully designed and synthesized via a one-pot Friedel–Crafts alkylation reaction.
Wu, Jia-Rui   +11 more
core   +2 more sources

Semi rigid connections and their influence on steel column behaviour. [PDF]

open access: yes, 1980
A review of the development of the analysis of frames with semi-rigid end restraint is given, including the treatment of frame stability and effective lengths. The available experimental data relating to the moment versus in-plane
Jones, Stephen Winford
core  

Semi-rigid hose

open access: yes, 2019
Semi-rigid ...
Glenda McMahon (1258275)   +1 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Wind-resistance and seismic behavior of a steel frame elevator with square hollow section members and semi-rigid joints

open access: yesFrontiers in Built Environment
This article presents a study of the wind-resistance and seismic behavior of steel frame elevator structures with square hollow section (SHS) members. The study was conducted by numerical analysis, it begins by examining the semi-rigid performance of SHS
Bi-Da Zhao   +8 more
doaj   +1 more source

Frame behaviour with semi-rigid connections. [PDF]

open access: yes, 1989
In this thesis both analytical and design studies have been conducted on the behaviour of fully and semi-rigidly connected multistorey steel frames.
Chikho, A.H., Chikho, Abdul Hakim
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The response of non-sway steel framed structures with semi-rigid connections. [PDF]

open access: yes, 1993
This thesis describes research work undertaken to examine the influence of joint resis- tance to in-plane moments on the assessment of five fun scale two dimensional steel frames.
Lau, Sui Ming, Lau, S.M.
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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