Results 91 to 100 of about 259,134 (247)

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang   +7 more
wiley   +1 more source

A Semi-Supervised Multi-Scale Convolutional Neural Network for Hyperspectral Image Classification with Limited Labeled Samples

open access: yesRemote Sensing
Supervised deep learning methods have been widely utilized in hyperspectral image (HSI) classification tasks. However, acquiring a large number of reliably labeled samples to train deep networks is not always possible in practical HSI applications due to
Chen Yang   +3 more
doaj   +1 more source

Long‐Term Elevated CO2 Improves Soil Health and Rice Yields in Paddy Fields

open access: yesAdvanced Science, EarlyView.
Combining the two longest‐running rice free‐air CO2 enrichment experiments with a global data synthesis, this study demonstrates that long‐term elevated CO2 consistently enhances soil health. In rice paddies, this improvement sustains the CO2 fertilization effect over decades.
Fan Jiang   +22 more
wiley   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu   +6 more
wiley   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

open access: yesAdvanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen   +12 more
wiley   +1 more source

SMILE: Semi-supervised multi-view classification based on dynamical fusion.

open access: yesPLoS ONE
Semi-supervised multi-view classification plays a crucial role in understanding and utilizing existing multi-view data, especially in domains like medical diagnosis and autonomous driving.
Hui Yang, Linyan Kang, Xun Che
doaj   +1 more source

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu   +14 more
wiley   +1 more source

Multi-Level Cross-Modal Interactive-Network-Based Semi-Supervised Multi-Modal Ship Classification

open access: yesSensors
Ship image classification identifies the type of ships in an input image, which plays a significant role in the marine field. To enhance the ship classification performance, various research focuses on studying multi-modal ship classification, which aims
Xin Song   +5 more
doaj   +1 more source

A semi-supervised machine learning framework for microRNA classification

open access: yesHuman Genomics, 2019
Background MicroRNAs (miRNAs) are a family of short, non-coding RNAs that have been linked to critical cellular activities, most notably regulation of gene expression.
Mohsen Sheikh Hassani, James R. Green
doaj   +1 more source

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