Results 41 to 50 of about 11,477 (218)

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

Advanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng, Jieyu Qi, Chen‐Chi Wu, Yilai Shu, Renjie Chai   +4 more
wiley   +1 more source

Differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis

Laryngoscope Investigative Otolaryngology, 2023
Objective To expand our understanding of the pathophysiological mechanisms underlying vestibular neuritis and labyrinthitis by identifying any difference in the vestibulo‐ocular reflex for each semicircular canal.
Gi‐Sung Nam, Wonyong Baek, Min Seok Kim, Sung Il Cho   +3 more
doaj   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Assessment of semicircular canal function in benign paroxysmal positional vertigo using the video head impulse test and caloric test

Laryngoscope Investigative Otolaryngology, 2023
Objective To assess semicircular canal function in benign paroxysmal positional vertigo (BPPV) using the video head impulse test (vHIT) and caloric test. Methods We retrospectively reviewed 39 patients with idiopathic BPPV who underwent both vHIT and the
Kayoko Kabaya, Sachiyo Katsumi, Akina Fukushima, Shinichi Esaki, Toshiya Minakata, Shinichi Iwasaki   +5 more
doaj   +1 more source

Bilateral Dysfunction of Otolith Pathway in Patients With Unilateral Idiopathic BPPV Detected by ACS-VEMPs

Frontiers in Neurology, 2022
ObjectiveTo observe the functional status of the otolith pathway in patients with unilateral idiopathic benign paroxysmal positional vertigo (BPPV) by combining air-conducted sound elicited cervical vestibular-evoked myogenic potential (ACS-cVEMP) and ...
Xiaorong Niu, Peng Han, Maoli Duan, Zichen Chen, Juan Hu, Yanfei Chen, Min Xu, Pengyu Ren, Qing Zhang, Qing Zhang   +9 more
doaj   +1 more source

A Robotic Urinary Bladder Enabling Volume Monitoring and Assisted Micturition

Advanced Intelligent Systems, EarlyView.
An implantable robotic bladder is presented that can store urine in an origami‐designed enclosure. An inductance sensing principle can monitor and transfer the urine volume in real‐time. It can actively expand based on the amount of urine collected from kidneys and apply on‐demand mechanical compression to assist urination.
Izadyar Tamadon, Michele Ibrahimi, Federica Semproni, Veronica Iacovacci, Arianna Menciassi   +4 more
wiley   +1 more source

Temporal bone histopathology: Superior semicircular canal dehiscence

Laryngoscope Investigative Otolaryngology, 2020
Objectives To present a histopathological case of a 91‐year‐old woman who was diagnosed with superior semicircular canal dehiscence postmortem. Methods The patient was a registered donor with the National Temporal Bone Donor Program at the NIDCD National
Brian M. Lin, Katherine Reinshagen, Joseph Nadol Jr, Alicia M. Quesnel   +3 more
doaj   +1 more source

Cupulolithiasis as an Alternative Mechanism for Pseudo-spontaneous Nystagmus in Horizontal Canal Benign Paroxysmal Positional Vertigo

OTO Open, 2022
Benign paroxysmal positional vertigo of the horizontal semicircular canal may present a differential diagnostic challenge. In addition to the classical positional nystagmus, a persistent nystagmus in a seated position occasionally occurs, so-called ...
Felix K. Schwarz MD, Erich Vyskocil MD, Bela Büki MD, PhD, Gerald Wiest MD   +3 more
doaj   +1 more source

Identification and Characterization of a Novel Biallelic SLC12A2 Variant Associated With Kilquist Syndrome (OMIM #619080)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study presents the case of a child with multiple congenital anomalies, severe hypotonia, and profound bilateral sensorineural hearing loss. Functional bioenergetic assessments showed no significant mitochondrial respiratory defects, and riboflavin (Rf) status evaluation excluded a deficiency in Rf transporters as a cause of hearing loss ...
Piero Leone, Alessia Nisco, Luciana de Gennaro, Maria Tolomeo, Elisa Lorefice, Giuseppe Petrosillo, Silvia Russo, Donatella De Giovanni, Claudia Rita Catacchio, Francesca Romana Lepri, Mario Ventura, Simonetta Simonetti, Albina Tummolo, Maria Barile   +13 more
wiley   +1 more source

Surgical Treatment for Recurrent Benign Paroxysmal Positional Vertigo

International Archives of Otorhinolaryngology, 2017
Introduction Benign paroxysmal positional vertigo is a generally benign condition that responds to repositioning maneuvers and frequently resolves spontaneously.
Gonzalo Corvera Behar, Miguel Alfredo García de la Cruz   +1 more
doaj   +1 more source