Advanced Materials Technologies, EarlyView.A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee +5 more
wiley +1 more source
Zinner's syndrome: A rare diagnosis of congenital seminal vesicle cyst and renal agenesis on basis of radiological imaging and its management. [PDF]
Int J Surg Case Rep, 2022 Regmi AR +5 more
europepmc +1 more source
Spermiogenesis in three species of cicadas (Hemiptera: Cicadidae) [PDF]
, 2007 Spermiogenesis in three species of cicadas representing one cicadettine (Monomatapa matoposa Boulard) and two cicadines (Diceroprocta biconica [Walker] and Kongota punctigera [Walker]) was investigated by light and electron microscopy.
Chawanji, A S +4 more
core +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Case Reports in Urology, 2011 Seminal vesicle cyst is an extremely rare disease. Its association with ipsilateral renal agenesis is even more exceptional. We present herein one case of a 16-year-old male who presented with a four-month history of lower urinary tract symptoms (LUTSs ...
Youness Ahallal +5 more
doaj +1 more source
Transperitoneal Laparoscopic Unroofing versus Fenestration Under Seminal Vesiculoscopy for Seminal Vesicle Cyst, a Multi-Institutional Retrospective Cohort Study. [PDF]
Int J Gen Med, 2022 Ding K +5 more
europepmc +1 more source
Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
Advanced Science, EarlyView.The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source
A rare case of Zinner syndrome: Triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst and ejaculatory duct obstruction. [PDF]
Radiol Case Rep, 2021 Karki P, Manandhar S, Kharel A.
europepmc +1 more source
A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis
Advanced Science, EarlyView.This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou +14 more
wiley +1 more source
Advanced Science, EarlyView.This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang +7 more
wiley +1 more source