Results 61 to 70 of about 4,147 (298)

Sonological evaluation of male infertility at tertiary care hospital [PDF]

New Indian Journal of OBGYN, 2018
Objectives: The aim of the study was to sonological evaluation of male infertility at pre-testicular, testicular and post-testicular levels. Material and methods: This study was conducted in the department of obstetrics and gynecology in collaboration ...
Umashankar KM, Jayeeta Mukerjee, BN Seal, SN Banerjee, Rizval Karim   +4 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

The giant seminal vesicle cyst: MRI findings.

Journal of the Belgian Society of Radiology, 2012
A 73-year-old man suffering from supra-pubic pain, dysuria and urinary retention for 3 months was slightly hypertensive, normoglycaemic, with normal renal biochemical parameters.
B Battal, V Akgun, B Karaman
doaj   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Zinner’s syndrome, radiological diagnosis for a rare syndrome with non-specific clinical presentation: case report

The Egyptian Journal of Radiology and Nuclear Medicine, 2020
Background Zinner’s syndrome is a rare congenital malformation involving the seminal vesicle that mostly shows cystic transformation. Embryogenesis of the kidney, ureter, seminal vesicle, and vas deferens can be altered if an insult occurs during the ...
Ahmed Atef Soliman, Anwar Ali Alshukami, Walaa Hussein AlZuber   +2 more
doaj   +1 more source

Blanks, a nuclear siRNA/dsRNA-binding complex component, is required for Drosophila spermiogenesis [PDF]

, 2011
Small RNAs and a diverse array of protein partners control gene expression in eukaryotes through a variety of mechanisms. By combining siRNA affinity chromatography and mass spectrometry, we have identified the double-stranded RNA-binding domain protein ...
Gerbasi, V. R., Preall, J. B., Golden, D. E., Powell, D. W., Cummins, T. D., Sontheimer, E. J.   +5 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Conservation of wild silkworm genetic resources through cryopreservation: Standardization of sperm processing [PDF]

, 2018
Conservation of the invaluable sericigenous genetic resources is of prime importance with respect to their utilization and improvement for wider exploitation.
Gargi, Gargi, Gowda, Veeranna, Lokesh, G., Murthy, Geetha N, Sahay, Alok   +4 more
core   +2 more sources

Control of Uterine Microenvironment by Foxp3+ Cells Facilitates Embryo Implantation [PDF]

, 2013
Implantation of the fertilized egg into the maternal uterus depends on the fine balance between inflammatory and anti-inflammatory processes. Whilst regulatory T cells (Tregs) are reportedly involved in protection of allogeneic fetuses against rejection ...
Hämmerling, Günter J., Kühnle, Marie-Cristine, Linzke, Nadja, Reichardt, Peter, Schumacher, Anne, Tadokoro, Carlos Eduardo, Teles, Ana, Thuere, Catharina, Zenclussen, Ana Claudia   +8 more
core   +1 more source