Results 111 to 120 of about 24,482 (261)

Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review [PDF]

open access: yes, 2016
Notwithstanding the peculiar sensitivity to cisplatin-based treatment, resulting in a very high percentage of cures even in advanced stages of the disease, still we do not know the biological mechanisms that make Testicular Germ Cell Tumor (TGCT) "unique"
Ametrano, Gianluca   +29 more
core   +1 more source

Update on management of seminoma

open access: yesIndian Journal of Urology, 2010
Testicular germ cell tumors and, in particular, seminomas are exquisitely radiation and chemotherapy-sensitive and most presentations are highly curable. In recent years the management focus has been on reducing late sequelae of treatment. For Stage I disease surveillance and adjuvant carboplatin, chemotherapy has become an option.
Alexander, EJ, White, IM, Horwich, A
openaire   +5 more sources

Antioxidant enzyme profile and lipid peroxidation products in semen samples of testicular germ cell tumor patients submitted to orchiectomy

open access: yesInternational Brazilian Journal of Urology
Purpose To determine enzymatic antioxidant and lipid peroxidation levels in seminal plasma of patients orchiectomized for testicular tumors. Materials and Methods The study included 52 patients: 26 control men and 26 orchiectomized patients for ...
Camila Sposito   +7 more
doaj   +1 more source

Seminoma primário do mediastino

open access: yesRevista Brasileira de Cancerologia, 2002
O seminoma primário de mediastino é uma neoplasia rara, principalmente em mulheres, nas quais existem apenas oito casos descritos de seminoma. Tem sua maior incidência entre a terceira e quarta décadas, caracterizando-se por grande radiossensibilidade ...
Cleverson Winston de Liz Medeiros   +5 more
doaj   +1 more source

Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]

open access: yes, 2017
BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.
Albany, Costantine   +5 more
core   +1 more source

Cytochrome P450 aromatase expression in human seminoma

open access: yesReproductive Biology and Endocrinology, 2005
Background The enzyme cytochrome P450 aromatase, catalysing the conversion of androgens into estrogens, has been detected in normal human testicular cells suggesting a physiological role of local estrogen biosynthesis on spermatogenesis control ...
Montanaro Daniela   +5 more
doaj   +1 more source

Technical performance and diagnostic utility of the new Elecsys (R) neuron-specific enolase enzyme immunoassay [PDF]

open access: yes, 2003
This international multicenter study was designed to evaluate the technical performance of the new double-monoclonal, single-step Elecsys neuron-specific enolase (NSE) enzyme immunoassay (EIA) and to assess its utility as a sensitive and specific test ...
Chang SF   +18 more
core   +1 more source

Mapping of succinate dehydrogenase losses in 2258 epithelial neoplasms. [PDF]

open access: yes, 2014
Losses in the succinate dehydrogenase (SDH) complex characterize 20% to 30% of extra-adrenal paragangliomas and 7% to 8% of gastric GISTs, and rare renal cell carcinomas.
Biernat, Wojciech   +9 more
core   +1 more source

Post-chemotherapy residual mass in stage IIC seminomatous testicular tumor [PDF]

open access: yes, 2002
Introduction The management of patients with residual masses following chemotherapy for advanced seminoma remains a difficult problem with no clear guidelines.
Abbas, Farhat, Ahmad, N A, Biyabani, S R
core   +1 more source

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