Results 111 to 120 of about 24,482 (261)
Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review [PDF]
Notwithstanding the peculiar sensitivity to cisplatin-based treatment, resulting in a very high percentage of cures even in advanced stages of the disease, still we do not know the biological mechanisms that make Testicular Germ Cell Tumor (TGCT) "unique"
Ametrano, Gianluca+29 more
core +1 more source
Update on management of seminoma
Testicular germ cell tumors and, in particular, seminomas are exquisitely radiation and chemotherapy-sensitive and most presentations are highly curable. In recent years the management focus has been on reducing late sequelae of treatment. For Stage I disease surveillance and adjuvant carboplatin, chemotherapy has become an option.
Alexander, EJ, White, IM, Horwich, A
openaire +5 more sources
Purpose To determine enzymatic antioxidant and lipid peroxidation levels in seminal plasma of patients orchiectomized for testicular tumors. Materials and Methods The study included 52 patients: 26 control men and 26 orchiectomized patients for ...
Camila Sposito+7 more
doaj +1 more source
Seminoma primário do mediastino
O seminoma primário de mediastino é uma neoplasia rara, principalmente em mulheres, nas quais existem apenas oito casos descritos de seminoma. Tem sua maior incidência entre a terceira e quarta décadas, caracterizando-se por grande radiossensibilidade ...
Cleverson Winston de Liz Medeiros+5 more
doaj +1 more source
Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]
BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.
Albany, Costantine+5 more
core +1 more source
Cytochrome P450 aromatase expression in human seminoma
Background The enzyme cytochrome P450 aromatase, catalysing the conversion of androgens into estrogens, has been detected in normal human testicular cells suggesting a physiological role of local estrogen biosynthesis on spermatogenesis control ...
Montanaro Daniela+5 more
doaj +1 more source
Technical performance and diagnostic utility of the new Elecsys (R) neuron-specific enolase enzyme immunoassay [PDF]
This international multicenter study was designed to evaluate the technical performance of the new double-monoclonal, single-step Elecsys neuron-specific enolase (NSE) enzyme immunoassay (EIA) and to assess its utility as a sensitive and specific test ...
Chang SF+18 more
core +1 more source
Seminoma Testis with Metastases After 31 Years [PDF]
Paul T. Strickland
openalex +1 more source
Mapping of succinate dehydrogenase losses in 2258 epithelial neoplasms. [PDF]
Losses in the succinate dehydrogenase (SDH) complex characterize 20% to 30% of extra-adrenal paragangliomas and 7% to 8% of gastric GISTs, and rare renal cell carcinomas.
Biernat, Wojciech+9 more
core +1 more source
Post-chemotherapy residual mass in stage IIC seminomatous testicular tumor [PDF]
Introduction The management of patients with residual masses following chemotherapy for advanced seminoma remains a difficult problem with no clear guidelines.
Abbas, Farhat, Ahmad, N A, Biyabani, S R
core +1 more source