Results 91 to 100 of about 862 (170)

Endoplasmic reticulum stress in diseases

MedComm, Volume 5, Issue 9, September 2024.
The endoplasmic reticulum (ER) serves as a vital organelle in eukaryotic cells, performing essential roles such as protein folding, modification, and trafficking, lipid biosynthesis, and calcium regulation. Various conditions may disrupt ER function, potentially leading to the accumulation of unfolded and misfolded proteins, and triggering ER stress ...
Yingying Liu, Chunling Xu, Renjun Gu, Ruiqin Han, Ziyun Li, Xianrong Xu   +5 more
wiley   +1 more source

Preliminary Evaluation of Protective Efficacy of Inactivated Senecavirus A on Pigs

Life, 2021
Senecavirus A (SVA), formerly known as Seneca Valley virus (SVV), causes vesicular symptoms in adult pigs and acute death of neonatal piglets. This pathogen has emerged in major swine producing countries around the world and caused significant economic ...
Yuwan Li, Yangyi Zhang, Yingxin Liao, Yawei Sun, Yang Ruan, Chenchen Liu, Mengru Zhang, Fangfang Li, Xiaowen Li, Shuangqi Fan, Lin Yi, Hongxing Ding, Mingqiu Zhao, Jindai Fan, Jinding Chen   +14 more
doaj   +1 more source

Limited availability of methods for the detection of xenotransplantation‐relevant viruses in veterinary laboratories

Xenotransplantation, Volume 31, Issue 3, May/June 2024.
Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley   +1 more source

Immune evasion strategies of Seneca Valley virus: mechanisms of host innate immune suppression

Agriculture Communications
Seneca Valley virus (SVV), an emerging picornavirus, poses a significant threat to the global swine industry. Innate immunity acts as the initial defense mechanism of host cells against viral infection.
Shijie Xie, Jingyu Yan, Bo Jiang, Jue Liu, Jiangwei Song   +4 more
doaj   +1 more source

Senecavirus A- a study in immunogenicity, seroprevalence, pathogenesis, and transmission [PDF]

, 2019
Senecavirus A (SVA), formerly known as Seneca Valley Virus, is a single-strand, positive-sense RNA virus of the family Picornaviridae associated with recent outbreaks of idiopathic vesicular disease and increased neonate mortality in several swine ...
Houston, Elizabeth Rose
core   +2 more sources

Senecavirus A: Pathogenicity and Interactions with Host Cell Death Pathway [PDF]

, 2019
Senecavirus A (SVA) is a positive sense single-strand RNA virus of the genus Senecavirus, family Picornaviridae. Senecavirus A is an emerging picornavirus of swine, which causes vesicular disease (VD) in pigs that is clinically indistinguishable from ...
Hoch Vieira Fernandes, Maureen
core   +1 more source

Isolamento do senecavirus a de suínos no Brasil e seleção de amostras para caracterização genética [PDF]

, 2022
O objetivo do presente trabalho foi realizar a reamplificação viral a partir de amostras de Senecavirus A isoladas em suínos no Brasil entre 2018 e 2021 e, selecionar, com base na distribuição geográfica e temporal, amostras representativas das cepas ...
Barbosa, Amanda de Oliveira, Gava, Danielle, Lima, Marcelo de, Ribeiro, Leonardo Clasen, Schafer, Rejane   +4 more
core  

Dexamethasone treatment did not exacerbate Seneca Valley virus infection in nursery-age pigs

BMC Veterinary Research, 2018
Background Senecavirus A, commonly known as Seneca Valley virus (SVV), is a picornavirus that has been infrequently associated with porcine idiopathic vesicular disease (PIVD).
Alexandra Buckley, Nestor Montiel, Baoqing Guo, Vikas Kulshreshtha, Albert van Geelen, Hai Hoang, Christopher Rademacher, Kyoung-Jin Yoon, Kelly Lager   +8 more
doaj   +1 more source

Senecavirus A: Epidemiology, Pathogenesis and Infection Dynamics [PDF]

, 2017
Senecavirus A (SVA) is a positive sense single-stranded virus that belongs to the genus Senecavirus within the family Picornaviridae. Senecavirus has been present in US swine population since 1988.
Joshi, Lok Raj
core   +1 more source

First-in-Human, First-in-Child Trial of Autologous MSCs Carrying the Oncolytic Virus Icovir-5 in Patients with Advanced Tumors [PDF]

, 2020
We present here the results of a first-in-human, first-in-child trial for patients with relapsed/refractory solid tumors using Celyvir, an advanced therapy medicine that combines autologous mesenchymal stem cells (MSCs) carrying an oncolytic adenovirus ...
Alemany, Ramón, Andión, Maitane, Bautista, Francisco, Garcia-Castro, Javier, González-Murillo, África, Hernández, Carmen, Lassaletta, Álvaro, López-Martín, José A, Madero, Luis, Melen, Gustavo, Moreno, Lucas, Ramírez, Manuel, Ruano, David   +12 more
core   +1 more source