Results 101 to 110 of about 862 (170)

Development and evaluation of a real-time RT-PCR and a field-deployable RT-insulated isothermal PCR for the detection of Seneca Valley virus

open access: yesBMC Veterinary Research, 2019
Background Seneca Valley virus (SVV) has emerged in multiple countries in recent years. SVV infection can cause vesicular lesions clinically indistinguishable from those caused by other vesicular disease viruses, such as foot-and-mouth disease virus ...
Jianqiang Zhang   +13 more
doaj   +1 more source

RIG-I is responsible for activation of type I interferon pathway in Seneca Valley virus-infected porcine cells to suppress viral replication

open access: yesVirology Journal, 2018
Background Retinoic acid-inducible gene I (RIG-I) is a key cytosolic receptor of the innate immune system. Seneca valley virus (SVV) is a newly emerging RNA virus that infects pigs causing significant economic losses in pig industry.
Pengfei Li   +9 more
doaj   +1 more source

Thermal Selection of Seneca Valley Virus Gives Rise to a Novel Thermostable Mutant [PDF]

open access: yes, 2020
This project aimed to improve the stability of the novel oncolytic virus, Seneca Valley virus (SVV). This was with the overarching goal of determining the residues and mutations thereof within the viral capsid that are responsible for capsid stability ...
McCarthy, Cormac
core  

Oncolytic viruses as therapeutic tools for pediatric brain tumors [PDF]

open access: yes, 2018
In recent years, we have seen an important progress in our comprehension of the molecular basis of pediatric brain tumors (PBTs). However, they still represent the main cause of death by disease in children.
Alonso, M.M. (Marta M.)   +6 more
core  

Development of a primary cell model derived from porcine dorsal soft palate for foot-and-mouth disease virus research and diagnosis [PDF]

open access: yes, 2023
Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals that has a significant socio-economic impact. One concern associated with this disease is the ability of its etiological agent, the FMD virus (FMDV), to persist in
Hägglund, Sara   +1 more
core  

The Strategy of Picornavirus Evading Host Antiviral Responses: Non-structural Proteins Suppress the Production of IFNs [PDF]

open access: yes, 2018
Viral infections trigger the innate immune system to produce interferons (IFNs), which play important role in host antiviral responses. Co-evolution of viruses with their hosts has favored development of various strategies to evade the effects of IFNs ...
Laszlo Stipkovits   +5 more
core   +1 more source

Challenges and Opportunities in Glioblastoma and Immunovirotherapy with Oncolytic Herpes Simplex Virus Type 1 [PDF]

open access: yes, 2023
This dissertation covers data from published and pre-published studies exploring challenges and opportunities in the treatment of malignant glioma with emphasis in glioblastoma and oncolytic immunovirotherapy with an oncolytic herpes simplex virus type 1
Estevez-Ordonez, Dagoberto
core  

Biennial Report 2019-2020 [PDF]

open access: yes, 2021
https://digitalcommons.memphis.edu/govpubs-tn-department-agriculture-annual-report/1000/thumbnail ...
Tennessee. Department of Agriculture.
core   +1 more source

Microarray-based breast cancer classification using logistic regression and beyond [PDF]

open access: yes, 2017
Cancer is a major global health problem with millions of new cancer cases emerging each year and millions of cancer-related deaths occurring per year. Breast cancer ranks as the first to affect women with the most disease-related cases being reported in ...
Francielly Morais Rodrigues da Costa
core  

Development and Evaluation of Vaccine Candidates for Senecavirus A [PDF]

open access: yes, 2019
Senecavirus A (SVA) has been associated with several outbreaks of vesicular disease (VD) since 2014 in major swine-producing countries around the world.
Sharma, Bishwas
core   +1 more source

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