Results 71 to 80 of about 862 (170)

Pathogenesis and control of Senecavirus A in swine [PDF]

open access: yes, 2020
Senecavirus A (SVA) is a nonenveloped, single-stranded, positive-sense RNA virus in the family Picornaviridae. It was first discovered as a cell culture contaminant in 2002 but had been identified in US swine samples dating back to the late 1980s.
Buckley, Alexandra Christine
core   +3 more sources

A novel RNA-based in situ hybridization to detect Seneca Valley virus in neonatal piglets and sows affected with vesicular disease. [PDF]

open access: yesPLoS ONE, 2017
Seneca Valley virus (SVV) is the causative agent of an emerging vesicular disease in swine, which is clinically indistinguishable from other vesicular diseases such as foot-and-mouth disease.
Talita P Resende   +2 more
doaj   +1 more source

Clinical Application of Oncolytic Viruses: A Systematic Review [PDF]

open access: yes, 2020
Leveraging the immune system to thwart cancer is not a novel strategy and has been explored via cancer vaccines and use of immunomodulators like interferons.
Chauhan, Aman, Cook, Mary
core   +2 more sources

Seneca Valley Virus 3Cpro Cleaves Heterogeneous Nuclear Ribonucleoprotein K to Facilitate Viral Replication

open access: yesFrontiers in Microbiology, 2022
Seneca Valley virus (SVV) has emerged as an important pathogen that is associated with idiopathic vesicular infection in pigs, causing a potential threat to the global swine industry.
Jiangwei Song   +4 more
doaj   +1 more source

Full-Length Genome Sequences of Senecavirus A from Recent Idiopathic Vesicular Disease Outbreaks in U.S. Swine [PDF]

open access: yes, 2015
Since July 2015, vesicular lesions affecting growing pigs and sows accompanied with neonatal mortality have been reported in multiple U.S. states. Senecavirus A has been consistently detected from these cases.
Chen, Qi   +15 more
core   +3 more sources

Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing.

open access: yesPLoS Pathogens, 2023
RNA viruses cause numerous infectious diseases in humans and animals. The crosstalk between RNA viruses and the innate DNA sensing pathways attracts increasing attention.
Ya Yan   +12 more
doaj   +1 more source

Seneca Valley Virus 3Cpro Mediates Cleavage and Redistribution of Nucleolin To Facilitate Viral Replication

open access: yesMicrobiology Spectrum, 2022
Seneca Valley virus (SVV) is a recently discovered pathogen that poses a significant threat to the global pig industry. It has been shown that many viruses are reliant on nucleocytoplasmic trafficking of nucleolin (NCL) for their own replication.
Jiangwei Song   +3 more
doaj   +1 more source

Senecavirus A seroprevalence and risk factors in United States pig farms [PDF]

open access: yes, 2022
Senecavirus A (SVA) is a non-enveloped, single-stranded, positive-sense RNA virus belonging to the Picornaviridae family. Senecavirus A is constantly associated with outbreaks of vesicular disease in pigs and has been reported in several countries ...
Corzo, Cesar A.   +5 more
core   +4 more sources

Isolation and full-genome sequencing of Seneca Valley virus in piglets from China, 2016 [PDF]

open access: yes, 2016
BACKGROUND: Seneca valley virus (SVV), a member of the Picornaviridae family, is a small non-enveloped RNA virus, that is linked to porcine idiopathic vesicular disease (PIVD).
Huanchun Chen   +4 more
core   +1 more source

The impact of hypoxia on oncolytic virotherapy [PDF]

open access: yes, 2011
The hypoxic tumor microenvironment plays significant roles in tumor cell metabolism and survival, tumor growth, and progression. Hypoxia modulates target genes in target cells mainly through an oxygen-sensing signaling pathway mediated by hypoxia ...
Sheng Guo, Z
core   +3 more sources

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