Results 81 to 90 of about 862 (170)

Controversies in NEN: An ENETS position statement on the treatment of patients with Grade 3 well‐differentiated neuroendocrine tumours of the gastro‐enteropancreatic tract

open access: yesJournal of Neuroendocrinology, Volume 37, Issue 12, December 2025.
Abstract Grade 3 neuroendocrine tumours (NET G3) represent approximately 20% of high‐grade neuroendocrine neoplasms, and the recent identification of this entity has given rise to many unanswered questions relating to clinical management. The prognosis for these patients is worse than for those with Grade 1–2 well‐differentiated NET, but better than ...
Mairéad G. McNamara   +11 more
wiley   +1 more source

Oncolytic Virotherapy in Glioma Tumors. [PDF]

open access: yes, 2020
Glioma tumors are one of the most devastating cancer types. Glioblastoma is the most advanced stage with the worst prognosis. Current therapies are still unable to provide an e ective cure.
Ayuso Sacido, Ángel   +4 more
core   +1 more source

Extracellular vesicles promote the infection and pathogenicity of Japanese encephalitis virus

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 1, January 2025.
Abstract Japanese encephalitis virus (JEV) is a neurotropic zoonotic pathogen that poses a serious threat to public health. Currently, there is no specific therapeutic agent available for JEV infection, primarily due to the complexity of its infection mechanism and pathogenesis.
Junyao Xiong   +14 more
wiley   +1 more source

Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction

open access: yesFrontiers in Immunology, 2020
Stress granules (SGs) are the sites of mRNA storage and related to the regulation of mRNA translation, which are dynamic structures in response to various environmental stresses and viral infections.
Wei Wen   +20 more
doaj   +1 more source

LncRNA 8244-ssc-miR-320-CCR7 Regulates IFN-β during SVA Infecting PK-15 Cells

open access: yesMicroorganisms, 2023
Seneca Valley virus (SVV), a member of the Picornaviridae family, is an oncolytic RNA virus that can cause idiopathic vesicular disease and increase mortality in newborn piglets.
Xiaoyu Tang   +5 more
doaj   +1 more source

Evaluation of methods for generating Senecavirus A virus-like particles utilizing the baculovirus expression vector system [PDF]

open access: yes, 2017
A recombinant subunit vaccine against Seneca Valley virus (SVV) would be valuable to the swine industry. Recent SVV outbreaks have raised concerns with national biosecurity.
English, Jennifer Lynn
core   +2 more sources

Innate sensing of picornavirus infection involves cGAS-STING-mediated antiviral responses triggered by mitochondrial DNA release.

open access: yesPLoS Pathogens, 2023
Cyclic GMP-AMP synthase (cGAS) plays a key role in the innate immune responses to both DNA and RNA virus infection. Here, we found that enterovirus 71 (EV-A71), Seneca Valley virus (SVV), and foot-and-mouth disease virus (FMDV) infection triggered ...
Huisheng Liu   +12 more
doaj   +1 more source

Mitigation Strategies for African Swine Fever Virus Biosecurity: From Virus Inactivation to Pig Health

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
The African swine fever virus (ASFV) is a major global threat affecting pork production and strengthening biosecurity practices is an urgent priority, especially given the paucity of effective vaccines and antiviral drugs. Mitigation strategies focused on virus inactivation play an important role in controlling ASFV and there is growing recognition ...
Joshua A. Jackman   +3 more
wiley   +1 more source

Picornavirus infection enhances aspartate by the SLC38A8 transporter to promote viral replication.

open access: yesPLoS Pathogens, 2023
Foot-and-mouth disease, a class of animal diseases, is caused by foot-and-mouth disease virus (FMDV). The metabolic changes during FMDV infection remain unclear. Here, PK-15 cells, serum, and tonsils infected with FMDV were analyzed by metabolomics.
Huisheng Liu   +7 more
doaj   +1 more source

CRISPR/Cas system and its application in the diagnosis of animal infectious diseases

open access: yesThe FASEB Journal, Volume 38, Issue 24, 31 December 2024.
CRISPR‐based diagnostic platforms have transformed the molecular diagnostic field due to their outstanding ultra‐sensitive nucleic acid detecting capabilities. In this review, we highlighted the application of currently available CRISPR integrated setups on the diagnosis of animal infectious diseases.
Hafiz Muhammad Hamza Rasool   +3 more
wiley   +1 more source

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