Results 121 to 130 of about 1,604 (242)

Dilin Rivayetinde Dilcilerin ve Nahivcilerin Takip Ettikleri Usûl (Sîbeveyhi Örneği) [PDF]

, 2016
Hadis âlimleri, âdil ve sika ravilerden rivayete son derece önem vererek ve takip ettikleri metot sayesinde sünneti şüphe ve şaibelerden temizlediler. Acaba Arap dili âlimleri, dil rivayetinde aynı hassasiyeti gösterdiler mi?
Gunayydi, Omar Adib
core  

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

Advanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang, Shaoji Zhao, Ziling Shao, Tao Luo, Baifu Peng, Yifan Liu, Jinning Ye, Jianjun Peng, Kaiyu Sun, Jianbo Xu   +9 more
wiley   +1 more source

The relationships among perceived stress, resilience, sleep quality and first-month retention of newly employed nurses: A cross-sectional survey. [PDF]

Nurs Open, 2023
Lin YE, Lin CT, Hu ML, Tzeng S, Chien LY.   +4 more
europepmc   +1 more source

ATATÜRK’ÜN MİLLÎ HÂKİMİYET ANLAYIŞI VE BUNUN YANSIMALARI

Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2008
Hâkimiyetin ilâhi kaynaklıolarak kabul edildiği OsmanlıDevleti’nde, Batı’nın da etkisi ve baskısıyla bu konuya ilişkin çeşitli tartışmalar yaşanmıştır.
Ferudun Ata
doaj  

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

[Book Review] Mehmet Ali Çalgan, Muhaddisler Muhteva Tenkidi Yaptı Mı? (İstanbul: Marmara Üniversitesi İlâhiyat Vakfı Yayınları, 2023), page 278, ISBN: 9789755486864

İslâm dininin kaynaklarından biri olan hadisler temelde iki önemli unsur olan sened ve metinden oluşmaktadır. Râvilerin isimlerinin yer aldığı bölüme sened, Hz.
Uçar, Ayşe
core   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

Advanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen, Shilin Zhang, Xiaojie Deng, Wenqiang Xie, Fen Xu, Jie Shen, Hua Liang   +6 more
wiley   +1 more source

Visible‐Light‐Mediated Lewis Acid‐Catalyzed Diradical Hydrogen Atom Transfer Reaction of Enamides

Advanced Science, EarlyView.
The Lewis acid catalysis was crucial for the success of the DHAT reaction of enamides by lowering the energy of the triplet excited state and modulating the reactivity of the formed diradical intermediate in a carbon‐to‐carbon 1,5‐DHAT and consequent cyclization that allows the functionalization of C(sp3)−H bonds to construct a variety of novel β ...
Yao Huang, Baoyu Yang, Xiang Zhou, Israel Fernández, Kexue Xia, Yang Xiong   +5 more
wiley   +1 more source

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu, Ziliang Nie, Xi Chen, Guangyu Ji, Yajing Zhang, Zhiqun Zhao, Yuhong Zhang, Xinlong Du, Zhenzhen Zhou, Jiayi Li, Yaozong Yang, Fengqi Sun, Zhibo Yan, Haiquan Lu   +13 more
wiley   +1 more source

Connections during Crisis: Adolescents’ social dynamics and mental health during COVID-19 [PDF]

Dev Psychol, 2021
Gadassi Polack R, Sened H, Aubé S, Zhang A, Joormann J, Kober H.   +5 more
europepmc   +2 more sources