Results 81 to 90 of about 1,556 (255)

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

[Geroscience in times of global pandemic by COVID-19]. [PDF]

open access: yesRev Esp Geriatr Gerontol, 2021
Castro-Fuentes R   +2 more
europepmc   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra   +5 more
wiley   +1 more source

DESARROLLO DE UNA SOPA DE VERDURAS BAJO APLICACIÓN DE TECNOLOGÍA SOUS-VIDE, PARA SENESCENTES. [PDF]

open access: yes, 2008
LA INVESTIGACIÓN PROPUESTA CORRESPONDE A UN PROYECTO DE PRE-DESARROLLO DE PRODUCTOS CON UNA CLARA ORIENTACIÓN APLICADA. LA PRINCIPAL CONTRIBUCIÓN DE ESTE PROYECTO DESDE EL PUNTO DE VISTA CIENTÍFICO TECNOLÓGICO, RADICA EN EL CLARO OBJETIVO DE APLICAR LOS ...
ZAMBRANO CORNEJO, DOLORES TRINIDAD
core   +1 more source

ESTUDO DAS ALTERAÇÕES MORFOFUNCIONAIS EM FIBROBLASTOS SENESCENTES NA PELE COM MELASMA [PDF]

open access: yes
O melasma é uma discromia hiperpigmentar multifatorial na qual o indivíduo, principalmente mulher em idade fértil, pode adquirir ao longo da vida. As manchas acastanhadas se encontram principalmente na pele do rosto.
Marlo, Andres   +3 more
core   +2 more sources

Evolution and structure of Artikutza, an 80-year-old beech forest in navarra (northern Spain) [PDF]

open access: yesMunibe Ciencias Naturales, 2009
Se ha estudiado la estructura forestal y la historia del hayedo de Artikutza. El objetivo ha sido analizar la evolución natural y recuperación del bosque tras 80 años sin intervenciones significativas.
Castro Gil, A.
doaj  

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns   +2 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

Células Senescentes: ¿Cuál es su efecto e importancia?

open access: yes
La senescencia es un proceso actualmente ineludible, se ve influenciado por una gran cantidad de factores externos e internos, generando células con una actividad metabólica reducida y una menor o prácticamente ausente capacidad de replicación, y con la ...
Martínez, Indira   +1 more
core   +1 more source

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