Results 21 to 30 of about 31,402 (125)

A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues

Nature Communications, 2021
Although cellular senescence drives multiple age-related co-morbidities through the senescence-associated secretory phenotype, in vivo senescent cell identification remains challenging.
D. Saul, R. Kosinsky, Elizabeth J. Atkinson, Madison L. Doolittle, Xu Zhang, N. LeBrasseur, R. Pignolo, P. Robbins, L. Niedernhofer, Y. Ikeno, D. Jurk, J. Passos, L. Hickson, A. Xue, D. Monroe, T. Tchkonia, J. Kirkland, J. Farr, S. Khosla   +18 more
semanticscholar   +1 more source

Decomposição e liberação de nitrogênio, fósforo e potássio de resíduos da cultura do feijoeiro Decomposition and release of nitrogen, phosphorus and potassium from residues of common bean crop

Revista Brasileira de Ciência do Solo, 2007
Este trabalho teve como objetivo mensurar a velocidade de decomposição e de liberação de nutrientes in situ de resíduos da cultura do feijoeiro (Phaseolus vulgaris L.).
Eduardo Chagas, Adelson Paulo Araújo, Marcelo Grandi Teixeira, José Guilherme Marinho Guerra   +3 more
doaj   +1 more source

Telomere dysfunction in ageing and age-related diseases

Nature Cell Biology, 2022
Ageing organisms accumulate senescent cells that are thought to contribute to body dysfunction. Telomere shortening and damage are recognized causes of cellular senescence and ageing.
F. Rossiello, D. Jurk, J. Passos, F. d’Adda di Fagagna   +3 more
semanticscholar   +1 more source

Mitochondrial dysfunction in cell senescence and aging

Journal of Clinical Investigation, 2022
Mitochondrial dysfunction and cell senescence are hallmarks of aging and are closely interconnected. Mitochondrial dysfunction, operationally defined as a decreased respiratory capacity per mitochondrion together with a decreased mitochondrial membrane ...
S. Miwa, Sonu Kashyap, E. Chini, T. von Zglinicki   +3 more
semanticscholar   +1 more source

Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway.

Immunity
Mitochondrial dysfunction is a hallmark of cellular senescence. Here, we investigated whether senescent cells release mitochondrial (mt)DNA into the extracellular space and its impact on innate immunity.
Ping‐Chang Lai, Lei Liu, Nicoló Bancaro, M. Troiani, B. Calí, Yuxin Li, Jingjing Chen, P. Singh, R. Arzola, Giuseppe Attanasio, N. Pernigoni, E. Pasquini, Simone Mosole, Andrea Rinaldi, Jacopo Sgrignani, Shi Qiu, Pan Song, Yingrui Li, M. A. Desbats, Azucena Rendón Ángel, R. P. Mestre, Andrea Cavalli, L. Barile, Johann de Bono, A. Alimonti   +24 more
semanticscholar   +1 more source

Senescence and cancer — role and therapeutic opportunities

Nature Reviews Clinical Oncology, 2022
Cellular senescence is a state of stable, terminal cell cycle arrest associated with various macromolecular changes and a hypersecretory, pro-inflammatory phenotype. Entry of cells into senescence can act as a barrier to tumorigenesis and, thus, could in
C. Schmitt, Boshi Wang, M. Demaria
semanticscholar   +1 more source

Mise en évidence d'anthocyanes dans les feuilles vertes de Cabernet Sauvignon

OENO One, 1986
Chez la Vigne, les feuilles des parties médiane et apicale des rameaux principaux jouent un rôle important dans l'apparition de la coloration anthocyanique des pellicules des raisins rouges (DARNÉ et GlORIES, 1986).
Gérard Darné
doaj   +1 more source

Quality of life among elderly participants in social centers: an integrative review / Qualidade de vida em idosos participantes de centros de convivência: uma revisão integrativa

Revista de Pesquisa Cuidado é Fundamental Online, 2021
Objetivo: analisar as produções científicas acerca da participação dos idosos integrantes de Centros de Convivência para Idosos e a influência destes na qualidade de vida dos participantes.
Anne Carolinne Marie dos Santos Gomes, Kaline De Araújo Medeiros, Ana Karla Maciel Soares, Rossana de Rocci Alves Barbosa Costa, Kay Francis Leal Vieira, Adriana Lira Rufino de Lucena   +5 more
doaj   +4 more sources

Guidelines for Minimal Information on Cellular Senescence Experimentation in vivo

Cell
Summary: Cellular senescence is a cell fate triggered in response to stress and is characterized by stable cell cycle arrest and a hypersecretory state. It has diverse biological roles, ranging from tissue repair to chronic disease.
M. Ogrodnik, Juan Carlos Acosta, Peter D. Adams, Fabrizio d'Adda di Fagagna, Darren J. Baker, C. Bishop, Tamir Chandra, Manuel Collado, Jesús Gil, Vassilis Gorgoulis, Florian Gruber, Eiji Hara, P. Jansen-Dürr, D. Jurk, S. Khosla, J. L. Kirkland, V. Krizhanovsky, Tohru Minamino, L. Niedernhofer, J. Passos, Nadja Anneliese Ruth Ring, Heinz Redl, P. D. Robbins, Francis Rodier, Karin Scharffetter-Kochanek, J. M. Sedivy, Ewa Sikora, K. Witwer, T. von Zglinicki, M. H. Yun, J. Grillari, M. Demaria   +31 more
semanticscholar   +1 more source

Quality of life among elderly participants in social centers: an integrative review / Qualidade de vida em idosos participantes de centros de convivência: uma revisão integrativa

Revista de Pesquisa Cuidado é Fundamental Online, 2020
Objetivo: analisar as produções científicas acerca da participação dos idosos integrantes de Centros de Convivência para Idosos e a influência destes na qualidade de vida dos participantes.
Anne Carolinne Marie dos Santos Gomes, Kaline De Araújo Medeiros, Ana Karla Maciel Soares, Rossana de Rocci Alves Barbosa Costa, Kay Francis Leal Vieira, Adriana Lira Rufino de Lucena   +5 more
doaj   +1 more source