Results 71 to 80 of about 1,611 (231)

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

[Geroscience in times of global pandemic by COVID-19]. [PDF]

Rev Esp Geriatr Gerontol, 2021
Castro-Fuentes R, Castro-Hernández J, Socas-Pérez R.   +2 more
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Evolution and structure of Artikutza, an 80-year-old beech forest in navarra (northern Spain) [PDF]

Munibe Ciencias Naturales, 2009
Se ha estudiado la estructura forestal y la historia del hayedo de Artikutza. El objetivo ha sido analizar la evolución natural y recuperación del bosque tras 80 años sin intervenciones significativas.
Castro Gil, A.
doaj  

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Actividad antialimentaria e insecticida de un extracto de hojas senescentes de Melia azedarach (Meliaceae) Antifeedant and insecticide activity of an extract from senescent leaves of Melia azedarach (Meliaceae)

Revista de la Sociedad Entomológica Argentina, 2003
Continuando con la búsqueda de nuevos insecticidas naturales obtenidos de plantas, se estudió la actividad de un extracto de hojas senescentes (amarillas) de Melia azedarach L. (Meliaceae).
Graciela Valladares, Lucas Garbin, María T. Defagó, Cecilia Carpinella, Sara Palacios   +4 more
doaj  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

EQUILÍBRIO ESTÁTICO E DINÂMICO EM INDIVÍDUOS SENESCENTES E O ÍNDICE DE MASSA CORPORAL [PDF]

, 2017
O estudo objetivou analisar o equilíbrio estático e o dinâmico em indivíduos senescentes e verificar sua associação com a idade e com o Índice de Massa Corporal (IMC).
Sako, Fernando Koiti, Aurichio, Thaís Rabiatti, Rebelatto, José Rubens, de Castro, Alessandra Paiva   +3 more
core  

Impacto da aplicação de efluente maturado de fecularia de mandioca em solo e na cultura do sorgo - DOI: 10.4025/actasciagron.v26i4.1801

Acta Scientiarum. Agronomy, 2008
O presente trabalho teve como objetivo avaliar o comportamento da cultura do sorgo submetida a doses de efluente maturado de fecularia de mandioca. Realizou-se o presente trabalho no Centro Técnico de Irrigação da Universidade Estadual de Maringá, Estado
Frederico Fonseca da Silva, Paulo Sérgio Lourenço Freitas, Altair Bertonha, Antonio Saraiva Muniz, Roberto Rezende   +4 more
doaj   +1 more source

Natural Variation in ZmASB1 Links Tryptophan Metabolism to Root Growth and Drought Tolerance in Maize

Advanced Science, EarlyView.
Natural variation in the maize ZmASB1 promoter regulates tryptophan accumulation, root development, and drought tolerance through a tryptophan–auxin pathway. A 5‐bp InDel alters ZmDOF17 binding and promoter activity, and the favorable allele is enriched during breeding. These findings reveal a cis‐regulatory mechanism linking amino acid metabolism with
Xiaoyi Yang, Houmiao Wang, Xiaomin Zhang, Yunyun Wang, Yimei Tian, Baoqing Wang, Tianze Zhu, Shuai Fang, Wei Li, Wenye Rui, Yining Zhang, Dan Sun, Haoxin Gao, Yuxuan Li, Zhongtao Jia, Zefeng Yang, Chenwu Xu, Pengcheng Li   +17 more
wiley   +1 more source