Results 251 to 260 of about 365,500 (282)

Senile plaques in Huntington's disease: A preliminary report

Clinical Neurology and Neurosurgery, 1990
The brains of 10 patients with Huntington's disease (HD) were studied for the presence of senile plaques (SP), neurofibrillary tangles, and granulovacuolar degeneration in the frontobasal, the parietal and occipital cortices and the anterior and posterior hippocampus. Five had died at a mean age of 42 years and 5 at one of 74 years. Senile plaques were
G.W. Bruyn, R.A.C. Roos
openaire   +2 more sources

Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: implications for disease pathogenesis.

Biochemical and Biophysical Research Communications - BBRC, 1995
Apolipoprotein E (ApoE) genotype is a significant risk factor for the development of Alzheimer disease (AD) and the ApoE protein is associated with senile plaques (SP) and neurofibrillary tangles (NFT), the pathological lesions of AD.
P. Richey, S. Siedlak, M. Smith, George Perry   +3 more
semanticscholar   +1 more source

Unfolding the nature of senile plaque amyloid

Neurobiology of Aging, 1986
Abstract Dennis Selkoe presents a convincing case for considering senile plaque amyloid, as opposed to the paired helical filaments of the tangle, as a distinct or specific feature of Alzheimer type but not other cerebral degenerative diseases. Whilst the precise nature and origin of the amyloid are still elusive, speculations inevitably abound and ...
Perry EK, Perry RH
openaire   +3 more sources

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

Neurology, 1992
P. Arriagada, J. Growdon, E. Hedley‐Whyte, B. Hyman   +3 more
semanticscholar   +1 more source

Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Nature Network Boston, 1996
D. Scheuner, C. Eckman, C. Eckman, M. Jensen, X. Song, M. Citron, N. Suzuki, T. Bird, J. Hardy, M. Hutton, W. Kukull, Eric B. Larson, E. Levy-Lahad, M. Viitanen, E. Peskind, P. Poorkaj, G. Schellenberg, R. Tanzi, W. Wasco, L. Lannfelt, D. Selkoe, S. Younkin   +21 more
semanticscholar   +1 more source

Copper, iron and zinc in Alzheimer's disease senile plaques

Journal of Neurological Sciences, 1998
Mark A. Lovell, J. D. Robertson, W. J. Teesdale, John L. Campbell, W. Markesbery   +4 more
semanticscholar   +1 more source

Pregnancy Zone Protein is Increased in the Alzheimer’s Disease Brain and Associates with Senile Plaques

Journal of Alzheimer's Disease, 2015
D. Nijholt, L. Ijsselstijn, M. M. van der Weiden, P. Zheng, P. S. Sillevis Smitt, P. Koudstaal, T. Luider, J. Kros   +7 more
semanticscholar   +1 more source

Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)

Neuron, 1994
T. Iwatsubo, A. Odaka, N. Suzuki, H. Mizusawa, N. Nukina, Y. Ihara   +5 more
semanticscholar   +1 more source

Calcified senile scleral plaques

Journal of Neuroradiology, 2009
J. Larsen, J. Gossner
openaire   +3 more sources

Senile Plaque Amyloid

2015
Kidd, Michael, Allsop, David, Landon, Michael   +2 more
openaire   +2 more sources